Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Vanadium

Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_6149-2

Definition

Vanadium, a member of group VB and in the 4th period of the periodic table, is a first transition series, d-block, grayish metallic element with an atomic number of 23 and forms different oxidation states of −1, 0, +2, +3, +4, and +5. In the oxidation states +3 (vanadic), +4 (vanadyl), and +5 (vanadate) being most common, the oxidation state +4 is most stable in biological systems. Vanadium is an endogenous constituent of most mammalian tissues and is further considered a dietary micronutrient. It is an essential element for the proper growth and development of mammals owing to its diverse physiological and biochemical functions.

Characteristics

The uniqueness of vanadium is that it is included in the list of 40 essential micronutrients required in small amounts for normal cell metabolism. Accordingly, it has been incorporated into many multinational pharmaceutical preparations for maintenance of normal health. Although micronutrients never have had pharmacological...

Keywords

Vanadium Compound Vanadium Complex Vanadium Treatment Murine Mammary Adenocarcinoma Regulatory Negative Feedback Loop 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. Chakraborty T, Chatterjee A, Rana A et al (2007) Carcinogen-induced early molecular events and its implication in the initiation of chemical hepatocarcinogenesis in rats: chemopreventive role of vanadium on this process. Biochim Biophys Acta 1772:48–59CrossRefPubMedGoogle Scholar
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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Department of Pharmaceutical TechnologyJadavpur UniversityCalcuttaIndia