Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Phytochemicals in Cancer Prevention

  • Andreas J. Gescher
  • Karen Brown
  • William P. Steward
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_4564-3

Synonyms

Definition

Phytochemicals are molecules which occur in the plant kingdom; the prefix phyto- is used in words related to botany. Strictly speaking, the term phytochemical encompasses compounds belonging to a large range of chemical classes, from essential minerals such as selenium to large organic molecules such as plant proteins, fats, and carbohydrates, which serve as nutrients. Most people would probably associate the term phytochemical with small non-nutrient organic molecules contained in edible fruits and vegetables. Representative examples of potentially cancer chemopreventive phytochemicals (with their dietary precursors in brackets) are genistein (soya), vitamin c (fruits, vegetables), β-carotene (fruits, vegetables), curcumin (curry spice turmeric), lycopene (tomatoes), and tea catechins such as epigallocatechin gallate (green tea), resveratrol (red grapes, other fruits), and apigenin (leafy vegetables) (see Fig. 1).

Keywords

Familial Adenomatous Polyposis Adenomatous Polyposis Coli Familial Adenomatous Polyposis Patient Epigallocatechin Gallate Tramp Mouse 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.

References

  1. Fortmann SP, Burda BU, Senger CA et al (2013) Vitamin and mineral supplements in the primary prevention of cardiovascular disease and cancer: an updated systematic evidence review for the US Preventive Services Task Force. Ann Intern Med 159:824–834CrossRefPubMedGoogle Scholar
  2. Omenn GS (1998) Chemoprevention of lung cancer: the rise and demise of beta-carotene. Annu Rev Public Health 19:73–99CrossRefPubMedGoogle Scholar
  3. Surh YJ (2003) Cancer chemoprevention with dietary phytochemicals. Nat Rev Cancer 3:768–780CrossRefPubMedGoogle Scholar
  4. World Cancer Research Fund International (2015) http://www.wcrf-uk.org/uk/our-research/our-continuous-update-project

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Andreas J. Gescher
    • 1
  • Karen Brown
    • 2
  • William P. Steward
    • 2
  1. 1.Department of Cancer Studies, Cancer Biomarkers and Prevention GroupUniversity of Leicester, LeicesterLeicesterUK
  2. 2.Department of Cancer StudiesUniversity of LeicesterLeicesterUK