Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Ovarian Cancer

Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_4295-3

Definition

The term ovarian cancer is used to describe a heterogeneous group of malignant tumors found in the ovary (there is also a wide assortment of benign tumors derived from the ovary). Ovarian cancer is the most lethal gynecological cancer in industrialized countries and is the sixth leading cause of cancer deaths in women worldwide. Ovarian cancer typically occurs in peri- and postmenopausal women, with an average of 54 years at diagnosis. Histologically, ovarian cancer is complex but can be broadly divided into epithelial ovarian cancer, which accounts for up to 90 % of all the ovarian malignancies, and non-epithelial tumors (sex-cord stromal tumors and ovarian germ cell tumors). Epithelial ovarian tumors have been assumed to be derived from the ovarian surface epithelium, but new evidence suggests that some of these tumors may actually originate from extraovarian tissues, such as the fallopian tube epithelium and endometrial tissue.

Characteristics

Pathology

Epithelial ovarian...

Keywords

Ovarian Cancer Epithelial Ovarian Cancer Lynch Syndrome Ovarian Surface Epithelium Ovarian Cancer Risk 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

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See Also

  1. (2012) Atypia. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 303. doi:10.1007/978-3-642-16483-5_449Google Scholar
  2. (2012) CA125. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, pp 577–578. doi:10.1007/978-3-642-16483-5_761Google Scholar
  3. (2012) Carboplatin. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 641. doi:10.1007/978-3-642-16483-5_833Google Scholar
  4. (2012) Choriocarcinoma. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 825. doi:10.1007/978-3-642-16483-5_6908Google Scholar
  5. (2012) Endometrioid Carcinoma. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1234. doi:10.1007/978-3-642-16483-5_6966Google Scholar
  6. (2012) Epithelial Ovarian Cancer. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1292. doi:10.1007/978-3-642-16483-5_6952Google Scholar
  7. (2012) DNA Repair. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1141. doi:10.1007/978-3-642-16483-5_1687Google Scholar
  8. (2012) Dysgerminoma. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1177. doi:10.1007/978-3-642-16483-5_1759Google Scholar
  9. (2012) HE4. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1636. doi:10.1007/978-3-642-16483-5_6998Google Scholar
  10. (2012) Monoclonal Antibody. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2367. doi:10.1007/978-3-642-16483-5_6842Google Scholar
  11. (2012) Ovarian Clear Cell Carcinoma. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2711. doi:10.1007/978-3-642-16483-5_6965Google Scholar
  12. (2012) Progression-Free Survival. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 3001. doi:10.1007/978-3-642-16483-5_6496Google Scholar
  13. (2012) Sertoli-Leydig Cell Tumor. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 3390. doi:10.1007/978-3-642-16483-5_5266Google Scholar
  14. (2012) Sex-Cord Stromal Tumors. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, pp 3395-3396. doi:10.1007/978-3-642-16483-5_5273Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.National Institute on Aging, NIHBaltimoreUSA
  2. 2.Laboratory of Cellular and Molecular BiologyNational Institute on Aging, NIHBaltimoreUSA