Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Anti-inflammatory Drugs

Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_307-2

Synonyms

Definition

Anti-inflammatory drugs include steroid and nonsteroidal anti-inflammatory drugs (also called NSAIDs). Generally, they are used to relieve clinical symptoms such as inflammation, swelling, stiffness, and pain.

Characteristics

Steroid Anti-inflammatory Drugs

Steroid anti-inflammatory drugs such as glucocorticoids are hormones naturally produced by the adrenal gland with a variety of important physiological activities within the body. They are prescribed for treatment of diseases such as adrenal insufficiency, arthritis, asthma, inflammatory bowel disease, transplant rejection, and the graft-versus-host disease. Glucocorticoids are also a very effective anticancer drug for childhood acute lymphoblastic leukemia (ALL), as well as in other lymphoid malignancies. The immune suppressive effect and anticancer therapy of glucocorticoids is mediated by the glucocorticoid receptors to specifically induce programmed cell death...

Keywords

Acute Lymphoblastic Leukemia Childhood Acute Lymphoblastic Leukemia Traditional NSAID Nsaid Treatment Cardiovascular Side Effect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. Grosch S, Maier TJ, Schiffmann S et al (2006) Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors. J Natl Cancer Inst 98:736–747CrossRefPubMedGoogle Scholar
  2. Jackson L, Evers BM (2006) Chronic inflammation and pathogenesis of GI and pancreatic cancers. Cancer Treat Res 130:39–65CrossRefPubMedGoogle Scholar
  3. Meric JB, Rottey S, Olaussen K et al (2006) Cyclooxygenase-2 as a target for anticancer drug development. Crit Rev Oncol Hematol 59:51–64CrossRefPubMedGoogle Scholar

See Also

  1. (2012) Cell division. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 738. doi:10.1007/978-3-642-16483-5_999Google Scholar
  2. (2012) Cyclooxygenase-2. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1035. doi:10.1007/978-3-642-16483-5_1435Google Scholar
  3. (2012) Glucocorticoids. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1558. doi:10.1007/978-3-642-16483-5_2429Google Scholar
  4. (2012) Inflammatory bowel disease. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1852. doi:10.1007/978-3-642-16483-5_6455Google Scholar
  5. (2012) Programmed cell death. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2994. doi:10.1007/978-3-642-16483-5_4760Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.The Chinese University of Hong KongHong KongChina