Early Genes of Human Papillomaviruses
Human Papillomavirus (HPV) 16 has six early genes that are transcribed from the same DNA strand. As in other viruses, the function of the early proteins is to alter several cellular events to guarantee the completion of the virus life cycle. In addition, three early proteins, E5, E6, and E7, are also involved in the induction of malignant transformation of the infected cells. The cutaneous HPV types have a similar organization of the early region, with exception that the majority of these types lack the E5.
KeywordsPocket Protein Long Control Region Beta HPV38 Pocket Protein Family Disc Large Protein
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