Encyclopedia of Astrobiology

Living Edition
| Editors: Muriel Gargaud, William M. Irvine, Ricardo Amils, Henderson James Cleaves, Daniele Pinti, José Cernicharo Quintanilla, Michel Viso

Proteome, Proteomics

Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27833-4_1289-3

Definition

A proteome is the complete set of proteins encoded by a genome. It is also defined as the proteincomplement of the genome. Whereas the proteome of a species is the whole set of potentially expressed proteins, the proteome of an individual organism displays variations according to the cell cycle, metabolic status, and environment-dependent variables. In multicellular organisms, the proteome is the subset of all encoded proteins which is expressed in a cell or tissue, also affected by the developmental stage and health of the organism. Proteomics is the field of molecular biology which studies the entire proteome for determining the structures and functions of the expressed proteins, as well as the relationships among them. Technologies widely used in proteomics include two-dimensional gel electrophoresis, mass spectrometry, techniques for structural characterization of proteins, and proteome-focused bioinformatic tools. In parallel to proteomics, other global and...

Keywords

Mass Spectrometry Developmental Stage Bioorganic Chemistry Technological Advance Interaction Network 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Centro de Astrobiología (CSIC/INTA)Consejo Superior de Investigaciones CientíficasTorrejon de Ardoz, MadridSpain