Manifestations of Malaria in Pregnancy
Maternal anemia (hemoglobin level <11 g/dL) due to malaria is a condition that is particularly prevalent in primigravidae who are nonimmune to pregnancy-specific Plasmodium strains. A study estimated that in holoendemic malaria regions with 5 % prevalence of severe anemia, there were approximately nine maternal deaths per 100,000 live births among primigravidae due to severe malarial anemia (Brabin et al. 2001). In Africa, malaria alone contributes up to 25 % of severe anemia cases involving pregnant women (Desai et al. 2007). Maternal anemia, whether due to malaria or other etiology, is a risk factor for intrauterine growth restriction (Scholl and Hediger 1994; Verhoeff et al. 2001).
Congenital malaria is the transmission of P. falciparum infection from maternal to fetal circulation through the placenta, which may take place during pregnancy or at the time of delivery (Menendez and Mayor 2007). The detection of asexual malaria parasites in the...
KeywordsHyaluronic Acid Chondroitin Sulfate Placental Malaria Severe Malarial Anemia Maternal Anemia
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