Soluble egg antigen preparations of Schistosoma mansoni and S. haematobium have been shown to have proliferative and genotoxic effects on tissues of their hosts. Examples are omega-1 protein of S. mansoni, IPSE/alpha-1 of S. mansoni, or several SEA preparations of S. haematobium.
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Honey J et al (2014) Controversies and challenges in research on urogenital schistosomiasis-associated bladder cancer. Trends Parasitol 30:324–332
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Mehlhorn, H. (2015). Soluble Egg Antigen (SEA). In: Mehlhorn, H. (eds) Encyclopedia of Parasitology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27769-6_2920-2
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DOI: https://doi.org/10.1007/978-3-642-27769-6_2920-2
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Publisher Name: Springer, Berlin, Heidelberg
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