Encyclopedia of Parasitology

Living Edition
| Editors: Heinz Mehlhorn

Leishmaniasis, Animals

Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27769-6_1727-2

Synonyms

Pathology

Leishmaniosis is caused by protozoa of the genus Leishmania that affect various mammalian hosts, but disease occurs most commonly in humans and dogs. The disease in dog is caused by L. infantum. The parasite is obligatory intracellular. It multiplies within macrophages and other cells of the mononuclear phagocytic system and causes chronic inflammatory processes. Clinically, the disease in dogs is characterized by a chronic loss of weight, nonregenerative anemia, intermittent pyrexia, and generalized or symmetrical lymphadenopathy. Cutaneous lesions are very common and include dry exfoliative dermatitis, nodules, ulcers, onychogryposis (clawlike curvature of the nails), and diffuse, symmetrical, or periorbital alopecia (Fig. 1). Ocular lesions such as keratoconjunctivitis, uveitis, and panophthalmitis may be present. Other signs include intermittent lameness, epistaxis, arthropathies, ascites, and intercurrent diarrhea. During postmortem examination,...

Keywords

Immune Response Inflammatory Process Postmortem Examination Cutaneous Lesion Mammalian Host 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.Institut für Zoomorphologie, Zellbiologie und ParasitologieHeinrich-Heine-UniversitätDüsseldorfGermany