Living Reference Work Entry

Encyclopedia of Microfluidics and Nanofluidics

pp 1-11

Date: Latest Version

Microscale Acoustofluidics

  • Barbaros CetinAffiliated withMechanical Engineering Department, Bilkent University Email author 
  • , Suleyman BuyukkocakAffiliated withDepartment of Mechanical Engineering, TOBB University of Economics and Technology
  • , Mehmet Bülent ÖzerAffiliated withDepartment of Mechanical Engineering, TOBB University of Economics and Technology

Synonyms

Acoustic separation; Acoustophoresis; Position manipulation of particles by ultrasonic fields; Ultrasonic particle separation

Definition

Microscale acoustofluidics defines the use of ultrasonic waves onto a fluid inside a microchannel. The acoustic waves are imposed on the fluid through excitation of the microchannel walls with an actuator. Acoustofluidics in microchannels is commonly used for moving and manipulating microparticles in a microchannel.

Overview

Separation of cells has several applications in medicine. In apheresis applications, certain types of cells in blood are separated from the remaining cells such as in leukapheresis, plateletpheresis, erythrocytapheresis, and plasmapheresis. The general methods used for separation of cell types are filtration which relies on separation due to size differences and the use of centrifugation which is separation through density differences. In order to prevent clogging of the filter, the filter is rinsed with a fluid flowing at a h ...

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