Cellular Automaton Modeling of Tumor Invasion
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Important class of transmembrane proteins. They play a significant role in cell-cell adhesion, ensuring that cells within tissues are bound together.
Motion response to chemical concentration gradients of a diffusive chemical substance.
- Extracellular matrix (ECM)
Components that are extracellular and composed of secreted fibrous proteins (e.g., collagen) and gel-like polysaccharides (e.g., glycosaminoglycans) binding cells and tissues together.
- Fiber tracts
Bundle of nerve fibers having a common origin, termination, and function within the spinal cord and brain.
Directed motion of cells along adhesion gradients of fixed substrates in the ECM, such as integrins.
- Slime trail motion
Cells secrete a nondiffusive substance; concentration gradients of the substance allow the cells to migrate toward already explored paths.
- Somatic evolution
Darwinian-type evolution that occurs on soma (as opposed to germ) cells and characterizes cancer progression...
We are grateful for generous support throughout the years by the Centre for Information Services and High Performance Computing, Dresden University of Technology, Germany.
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