Encyclopedia of Complexity and Systems Science

Living Edition
| Editors: Robert A. Meyers

DNA-Templated Self-Assembly of Protein Arrays and Highly Conductive Nanowires

Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27737-5_132-3

Definition of the Subject

DNA self-assembly is a very useful and powerful tool for bottom-up nanofabrication. It consists of combining unusual DNA motifs by specific structurally well-defined cohesive interactions (sticky ends) to produce target materials with predictable 3D structure. This method has generated versatile DNA nanostructures including polyhedral catenanes, robust nanomechanical devices, and a variety of periodic and aperiodic arrays in two dimensions. DNA-self-assembled structures have been used as the template for different guest functional molecules such as proteins, metallic nanoparticles, DNA-based nano-devices, and highly conductive nanowires. Regular lattices made of DNA could hold copies of large biological molecules in a highly ordered array for X-ray crystallography to determine their structure, an important step in the “rational” design of drugs. Alternatively, the lattices could serve as scaffolding for nanoelectronic components, either as a working device or...

Keywords

Stem Loop Conductive Nanowires Staple Strand Streptavidin Interaction Cross Tile 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Molecular FoundryLawrence Berkeley National LabBerkeleyUSA
  2. 2.Department of Chemistry and Biochemistry and Biodesign InstituteArizona State UniversityTempeUSA