Skin Mycosis

Living reference work entry

Abstract

Fungal infections of the skin account for a large number of consultations to general practitioners and dermatologists. They are caused by dermatophytes, such as Trichophyton rubrum, Trichophyton tonsurans, Trichophyton mentagrophytes, Microsporum canis, Epidermophyton floccosum, Microsporum gypseum, and Trichophyton verrucosum (Sinski and Kelley 1991).

Keywords

Triamcinolone Acetonide Skin Penetration Tinea Pedis Trichophyton Rubrum Trichophyton Mentagrophytes 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References and Further Reading

General Considerations

  1. Gupta AK, Sauder DN, Shear NH (1994) Continuing medical education. Antifungal agents: an overview. Part I and II. J Am Acad Dermatol 30(677–698):911–933CrossRefPubMedGoogle Scholar
  2. Sinski JT, Kelley LM (1991) A survey of dermatophytes from human patients in the United States from 1985–1987. Mycopathologia 114:117–126CrossRefPubMedGoogle Scholar

In Vitro Inhibitory Activity

  1. Dittmar W, Lohaus G (1973) HOE296, a new antimycotic compound with a broad antimicrobial spectrum. Arzneim Forsch/Drug Res 23:670–674Google Scholar
  2. Dittmar W, Grau W, Raether W, Schrinner E, Wagner WH (1981) Mikrobiologische Laboruntersuchungen mit Ciclopiroxolamin (Microbiological laboratory studies with cicloprirox olamine). Arzneim Forsch/Drug Res 31:1317–1322Google Scholar

In Vivo Activity in the Guinea Pig Trichophytosis Model

  1. Arika T, Hase T, Yokoo M (1993) Anti-Trichophyton mentagrophytes activity and percutaneous permeation of butenafine in guinea pigs. Antimicrob Agents Chemother 37:363–365CrossRefPubMedCentralPubMedGoogle Scholar
  2. Dittmar W, Grau W, Raether W, Schrinner E, Wagner WH (1981) Mikrobiologische Laboruntersuchungen mit Ciclopiroxolamin (Microbiological laboratory studies with cicloprirox olamine). Arzneim Forsch/Drug Res 31:1317–1322Google Scholar
  3. Garcia Rafanell J, Dronda MA, Merlos M, Forn J, Torres JM, Zapatero MI, Basi N (1992) In vitro and in vivo studies with flutrimazole, a new imidazole derivative with antifungal activity. Arzneim Forsch/Drug Res 42:836–840Google Scholar
  4. Millberger HJ, Gillert KE (1973) Induction of chronic trichophytosis in small experimental animals for testing antimycotics. II. Effect of triamcinolone acetonide in experimental guinea pig trichophytosis. Z Hautkr 48:637–6421PubMedGoogle Scholar
  5. Petranyi G, Meingassner JG, Mieth H (1987) Activity of terbinafine in experimental fungal infections of laboratory animals. Antimicrob Agents Chemother 31:1558–1561CrossRefPubMedCentralPubMedGoogle Scholar
  6. Plempel M, Regel E, Büchel KH (1983) Antimycotic efficacy of bifonazole in vitro and in vivo. Arzneim Forsch/Drug Res 33:517–524Google Scholar
  7. Schaude M, Petranyi G, Ackerbauer H, Meingassner JG, Mieth H (1990) Preclinical antimycotic activity of SDZ-485: a new orally and topically effective triazole. J Med Vet Mycol 28:445–454CrossRefPubMedGoogle Scholar

Skin Penetration

  1. Ceschin-Roques CG, Hänel H, Pruja-Bougaret SM, Lagarde I, Vandermander J, Michel G (1991) Ciclopirox cream 1 %: in vitro and in vivo penetration into the stratum corneum. Skin Pharmacol 4:95–99CrossRefPubMedGoogle Scholar
  2. Dittmar W (1981) Zur Penetration und antimyzetischen Wirksamkeit von Ciclopiroxolamin in verhorntem Körpergewebe (Penetration and antifungal activity of ciclopirox olamine in hornified tissue). Arzneim Forsch/Drug Res 31:1353–1356Google Scholar
  3. Hänel H, Raether W, Dittmar W (1988) Evaluation of fungicidal action and in a skin model considering the influence of penetration kinetics of various standard antimycotics. Ann N Y Acad Sci 544:329–337CrossRefPubMedGoogle Scholar
  4. Kligman AM, McGinley KJ, Foglia A (1987) An in vitro human skin model for assaying topical drugs against dermatophytic fungi. Acta Derm Venereol (Stockh) 67:243–248Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Department of DermatologyUC San FranciscoSan FranciscoUSA

Personalised recommendations