Transgenic Animals

Reference work entry

Abstract

Safety pharmacology studies are defined as:

“Those studies that investigate the potential undesirable pharmacodynamic effects of a substance on physiological functions in relation to exposure in the therapeutic range and above.” (ICH S7A International Guidelines on Safety Pharmacology Studies; Anon 2001)

Keywords

Transgenic Animal Conditional Knockout Hair Cell Loss Wellcome Trust Sanger Institute Safety Pharmacology 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References and Further Reading

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Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  1. 1.Safety Pharmacology Department, Global Safety AssessmentAstraZeneca R&DCheshireUnited Kingdom

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