Definition
These are rare tumors arising from the middle ear mucosa. They may be primary glandular lesions or metastatic from distant sites.
Etiology
These are very rare tumors that may or may not develop on top of previous chronic otitis media (Schmoldt et al. 1990; Morita et al. 1994). Metastatic adenocarcinomas have also been described from the stomach, colon, lung, prostate, breast, vagina, and other sites (Marques et al. 2002; Hosokawa et al. 2007; Chang et al. 2009; Owers et al. 2010).
Clinical Presentation
Patients may variably present with a friable bleeding mass in the external auditory meatus, erosion of the mastoid bone, and various neurotological signs and symptoms depending on the extent of invasion of the lesion. In some cases a vascular mass behind an intact tympanic membrane may mimic a paraganglioma. Diagnosis is usually delayed as the symptoms are usually confused with common infectious otological conditions. A history of persistent otorrhea (with or without...
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References
Chang KH, Song CE, Seo JH, Yeo SW (2009) Solitary metastasis of bronchogenic adenocarcinoma to the internal auditory canal: a case report. J Korean Med Sci 24:1227–1229
Glasscock ME 3rd, McKennan KX, Levine SC, Jackson CG (1987) Primary adenocarcinoma of the middle ear and temporal bone. Arch Otolaryngol Head Neck Surg 113(8):822–824
Goebel JA, Smith PG, Kemink JL, Graham MD (1987) Primary adenocarcinoma of the temporal bone mimicking paragangliomas: radiographic and clinical recognition. Otolaryngol Head Neck Surg 96(3):231–238
Hosokawa K, Mizuta S, Iwasaki S, Araki ST, Mineta H (2007) A rare case of metastasis to the temporal bone from prostate adenocarcinoma. Int J Head Neck Surg 1(2)
Marioni G, de Filippis C, Stramare R, Puggina S, Marino F, Ferran-Bennström E, Staffieri A (2001) Intracranial invasion from primary adenocarcinoma arising in the external and middle ear. Otorhinolaryngol Nova 11:308–313
Marques E, Brandis A, Samii M, Tatagiba M (2002) Late metastasis of breast adenocarcinoma Into internal auditory canal and cerebellopontine angle: case report. Arq Neuropsiquiatr 60(3-A):639–642
Morita M, Mori N, Takashima H, Miki H, Sakai SI (1994) Primary poorly differentiated adenocarcinoma of the middle ear. Auris Nasus Larynx 21(1):59–63
Owers CE, Stewart DJ, Stone J, Kelty CJ (2010) Hearing loss as an unusual consequence of metastatic gastric adenocarcinoma. J Surg Case Rep 8:6
Paulus W, Romstöck J, Weidenbecher M, Huk WJ, Fahlbusch R (1999) Middle ear adenocarcinoma with intracranial extension. Case report. J Neurosurg 90(3):555–558
Saliba I, Evrard AS (2009) Middle ear glandular neoplasms: adenoma, carcinoma or adenoma with neuroendocrine differentiation: a case series. Cases J 2:6508
Schmoldt U, Isecke E, Rohmann K (1990) Primary adenocarcinoma of the middle ear. Laryngorhinootologie 69(2):77–79
Shailendra S, Elmuntser A, Philip R, Prepageran N (2008) High grade mucoepidermoid carcinoma of the middle ear treated with extended temporal bone resection. Med J Malaysia 63(3):247–248
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Mostafa, B.E. (2013). Adenocarcinoma of Middle Ear. In: Kountakis, S.E. (eds) Encyclopedia of Otolaryngology, Head and Neck Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-23499-6_565
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DOI: https://doi.org/10.1007/978-3-642-23499-6_565
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-23498-9
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