Skip to main content

Definition

These are rare tumors arising from the middle ear mucosa. They may be primary glandular lesions or metastatic from distant sites.

Etiology

These are very rare tumors that may or may not develop on top of previous chronic otitis media (Schmoldt et al. 1990; Morita et al. 1994). Metastatic adenocarcinomas have also been described from the stomach, colon, lung, prostate, breast, vagina, and other sites (Marques et al. 2002; Hosokawa et al. 2007; Chang et al. 2009; Owers et al. 2010).

Clinical Presentation

Patients may variably present with a friable bleeding mass in the external auditory meatus, erosion of the mastoid bone, and various neurotological signs and symptoms depending on the extent of invasion of the lesion. In some cases a vascular mass behind an intact tympanic membrane may mimic a paraganglioma. Diagnosis is usually delayed as the symptoms are usually confused with common infectious otological conditions. A history of persistent otorrhea (with or without...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 2,300.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 2,999.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Chang KH, Song CE, Seo JH, Yeo SW (2009) Solitary metastasis of bronchogenic adenocarcinoma to the internal auditory canal: a case report. J Korean Med Sci 24:1227–1229

    Article  PubMed  Google Scholar 

  • Glasscock ME 3rd, McKennan KX, Levine SC, Jackson CG (1987) Primary adenocarcinoma of the middle ear and temporal bone. Arch Otolaryngol Head Neck Surg 113(8):822–824

    Article  PubMed  Google Scholar 

  • Goebel JA, Smith PG, Kemink JL, Graham MD (1987) Primary adenocarcinoma of the temporal bone mimicking paragangliomas: radiographic and clinical recognition. Otolaryngol Head Neck Surg 96(3):231–238

    PubMed  CAS  Google Scholar 

  • Hosokawa K, Mizuta S, Iwasaki S, Araki ST, Mineta H (2007) A rare case of metastasis to the temporal bone from prostate adenocarcinoma. Int J Head Neck Surg 1(2)

    Google Scholar 

  • Marioni G, de Filippis C, Stramare R, Puggina S, Marino F, Ferran-Bennström E, Staffieri A (2001) Intracranial invasion from primary adenocarcinoma arising in the external and middle ear. Otorhinolaryngol Nova 11:308–313

    Article  Google Scholar 

  • Marques E, Brandis A, Samii M, Tatagiba M (2002) Late metastasis of breast adenocarcinoma Into internal auditory canal and cerebellopontine angle: case report. Arq Neuropsiquiatr 60(3-A):639–642

    Article  PubMed  Google Scholar 

  • Morita M, Mori N, Takashima H, Miki H, Sakai SI (1994) Primary poorly differentiated adenocarcinoma of the middle ear. Auris Nasus Larynx 21(1):59–63

    Article  PubMed  CAS  Google Scholar 

  • Owers CE, Stewart DJ, Stone J, Kelty CJ (2010) Hearing loss as an unusual consequence of metastatic gastric adenocarcinoma. J Surg Case Rep 8:6

    Google Scholar 

  • Paulus W, Romstöck J, Weidenbecher M, Huk WJ, Fahlbusch R (1999) Middle ear adenocarcinoma with intracranial extension. Case report. J Neurosurg 90(3):555–558

    Article  PubMed  CAS  Google Scholar 

  • Saliba I, Evrard AS (2009) Middle ear glandular neoplasms: adenoma, carcinoma or adenoma with neuroendocrine differentiation: a case series. Cases J 2:6508

    Article  PubMed  Google Scholar 

  • Schmoldt U, Isecke E, Rohmann K (1990) Primary adenocarcinoma of the middle ear. Laryngorhinootologie 69(2):77–79

    Article  PubMed  CAS  Google Scholar 

  • Shailendra S, Elmuntser A, Philip R, Prepageran N (2008) High grade mucoepidermoid carcinoma of the middle ear treated with extended temporal bone resection. Med J Malaysia 63(3):247–248

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Badr Eldin Mostafa .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag Berlin Heidelberg

About this entry

Cite this entry

Mostafa, B.E. (2013). Adenocarcinoma of Middle Ear. In: Kountakis, S.E. (eds) Encyclopedia of Otolaryngology, Head and Neck Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-23499-6_565

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-23499-6_565

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-23498-9

  • Online ISBN: 978-3-642-23499-6

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics