Encyclopedia of Cancer

2011 Edition
| Editors: Manfred Schwab

Lung Cancer Epidemiology

  • Robert Kratzke
  • Michael J. Franklin
Reference work entry
DOI: https://doi.org/10.1007/978-3-642-16483-5_6893

Characteristics

Of all cancer types,  lung cancer is the leading cause of cancer-related death both worldwide and in the United States [1].

Types of Lung Cancer

Lung cancer accounts for 13% of all cancers diagnosed worldwide, making it the most commonly occurring malignancy other than non-melanoma  skin cancer [ 2]. Approximately 97% of primary lung cancers are carcinomas of the lung, arising from deregulated growth of  epithelial cells. The two major lung carcinomas are  non-small cell lung cancer (NSCLC) and  small cell lung cancer (SCLC). Approximately 80–85% of lung cancers are diagnosed as NSCLC, a heterogeneous group of malignancies consisting of three sub types:

The remaining 15–20% of lung cancers are diagnosed as small cell lung cancer (SCLC), a highly aggressive tumor. Besides these carcinomas, other cancers of the lung include  carcinoid tumors (synonym  carcinoid) and  sarcoma, accounting for only 1% of all lung...

This is a preview of subscription content, log in to check access.

References

  1. 1.
    Adami HO, Hunter D, Trichopoulos D (eds) (2002) Textbook of cancer epidemiology. Oxford University Press, New YorkGoogle Scholar
  2. 2.
    World Health Organization (2003) International agency for research on cancer (IARC): world cancer report. IARC Press, LyonGoogle Scholar
  3. 3.
    Ferlay J, Shin HR, Bray F et al. (2010) GLOBOCAN 2008, cancer incidence and mortality worldwide: IARC CancerBase No. 10 [Internet]. International Agency for Research on Cancer, Lyon. http://globocan.iarc.fr
  4. 4.
    Zhang H, Cai B (2003) The impact of tobacco on lung health in China. Respirology 8(1):17–21PubMedCrossRefGoogle Scholar
  5. 5.
    Altekruse SF, Kosary CL, Krapcho M et al (eds) (2010) SEER cancer statistics review, 1975–2007. National Cancer Institute, Bethesda. http://seer.cancer.gov/csr/1975_2007/, based on November 2009 SEER data submission, posted to the SEER web site, 2010
  6. 6.
    U.S. Department of Health and Human Services (2001) Women and smoking. A report of the surgeon general – 2001 U.S. Department of Human Services, CDCGoogle Scholar
  7. 7.
    Jemal A, Clegg L, Ward E, et al (2004) Annual report to the nation on the status of cancer, 1975–2001. American Cancer Society, National Cancer Institute, North American Association of Central Cancer Registries, Centers for Disease Control and Prevention, AtlantaGoogle Scholar
  8. 8.
    Albert AJ, Samet JM (2003) Epidemiology of lung cancer. Chest 123:21S–49SCrossRefGoogle Scholar
  9. 9.
    Bain C, Feskanich D, Speizer FE et al (2004) Lung cancer rates in men and women with comparable histories of smoking. J Natl Cancer Inst 96(11):826–833PubMedCrossRefGoogle Scholar
  10. 10.
    Doll R, Peto R (1978) Cigarette smoking and bronchial carcinoma: dose and time relationships among regular smokers and lifelong non-smokers. J Epidemiol Community Health 32(4):303–313PubMedPubMedCentralCrossRefGoogle Scholar
  11. 11.
    International Agency for Research on Cancer (2003) IARC monographs on the evaluation of carcinogenic risk in humans, vol 83, Tobacco smoking and involuntary smoking. IARC Press, LyonsGoogle Scholar
  12. 12.
    Giovino GA (2002) Epidemiology of tobacco use in the United States. Oncogene 21(48):7326–7340PubMedCrossRefGoogle Scholar
  13. 13.
    McLaughlin JK, Hrubec Z, Blot WJ, Fraumeni JF Jr (1995) Smoking and cancer mortality among U.S. veterans: a 26-year follow-up. Int J Cancer 60(2):190–193PubMedCrossRefGoogle Scholar
  14. 14.
    Nicholson WJ, Perkel G, Selikoff IJ (1982) Occupational exposure to asbestos: population at risk and projected mortality – 1980–2030. Am J Ind Med 3(3):259–311PubMedCrossRefGoogle Scholar
  15. 15.
    Rugo HS, Fischman ML (1997) Occupational cancer. In: LaDou J (ed) Occupational and environmental medicine. Appleton & Lange, Stamford, pp 235–271Google Scholar
  16. 16.
    Steenland K, Loomis D, Shy C et al (1996) Review of occupational lung carcinogens. Am J Ind Med 29(5):474–490PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Robert Kratzke
    • 1
  • Michael J. Franklin
    • 1
  1. 1.Division of Hematology, Oncology and TransplantationUniversity of MinnesotaMinneapolisUSA