Encyclopedia of Cancer

2011 Edition
| Editors: Manfred Schwab

Afinitor

Reference work entry
DOI: https://doi.org/10.1007/978-3-642-16483-5_6594

Definition

Brand name for RAD001( Everolimus) marketed by NOVARTIS. AFINITOR is a once-daily oral inhibitor of mTOR ( Mammalian Target of Rapamycin) for patients with advanced renal cell carcinoma (RCC;  Renal Cancer) whose disease has progressed on or after treatment with  Sorafenib or  Sunitinib therapy targeting  Vascular Endothelial Growth Factor (VEGF).

Copyright information

© Springer-Verlag Berlin Heidelberg 2011