Vinca Alkaloids
Reference work entry
First Online:
DOI: https://doi.org/10.1007/978-3-642-16483-5_6187
Definition
A class of chemotherapeutic drugs that disrupts mitosis by binding to tubulin, thus preventing microtubules from forming. These are also known as anti-mitotic, antimicrotubule agents, or mitosis inhibitors. Common vinca alkaloids include vinblastine, vincristine, vindesine, and vinorelbine.
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© Springer-Verlag Berlin Heidelberg 2011