Reference Work Entry

Encyclopedia of Cancer

pp 3800-3800

Date:

Tumor Stroma

Definition

Tumor microenvironment​ that is largely a product of the host and is induced as the result of tumor cell–host interactions. Stroma consists of non malignant supporting tissues with extracellular matrix and includes connective tissue, blood vessels, and inflammatory cells. It is essential for the growth of the tumor and its ability to progress and metastasize.

Stromagenesis

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© Springer-Verlag Berlin Heidelberg 2011
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