BAD
Reference work entry
First Online:
DOI: https://doi.org/10.1007/978-3-642-16483-5_519
Definition
BAD is a Bcl-2 antagonist of apoptosis/death, a pro-apoptotic member of the Bcl-2 family of proteins. It is a 18 kD protein that binds to Bcl-xL and Bcl-2. It competes out the binding of Bcl-xL and Bcl-2 to Bax, thus promoting apoptosis.
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© Springer-Verlag Berlin Heidelberg 2011