Encyclopedia of Cancer

2011 Edition
| Editors: Manfred Schwab

Pharmacokinetics

Reference work entry
DOI: https://doi.org/10.1007/978-3-642-16483-5_4500

Definition

PK; Is the study of how a drug is absorbed, distributed, metabolised, and excreted over time. Refers to what the body does to a drug, refers to the movement of drug into, through, and out of the body – the time course of its absorption, bioavailability, distribution, metabolism, and excretion. Pharmacodynamics ( Pharmacodynamics), described as what a drug does to the body, involves  receptor binding, postreceptor effects, and chemical interactions. Drug pharmacokinetics determines the onset, duration, and intensity of a drug’s effect. Formulas relating these processes summarize the pharmacokinetic behavior of most drugs.

Copyright information

© Springer-Verlag Berlin Heidelberg 2011