PDZ Ligand
Reference work entry
First Online:
DOI: https://doi.org/10.1007/978-3-642-16483-5_4429
Definition
A small peptide sequence (4–6 amino acids) that binds to PDZ domains, which are peptide-binding modules, and is usually embedded in large scaffolding proteins along with additional PDZ domains and/or peptide-binding modules. PDZ domains function to assemble their ligands into large complexes with other scaffold-associated molecules.
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