In  genetics, hybridization is the process by which two genetically unrelated parents – belonging to different strains, varieties,  species, or even genera – are crossed or mated to originate a hybrid organism. For example, a mule is a hybrid animal produced by crossing a female horse with a male donkey, whereas the grapefruit is a hybrid between a sweet orange and a pomelo. In turn, in molecular biology, hybridization is the process by which two biomolecules or fragments of them interact specifically with each other.  Nucleic acid hybridization is the process of annealing two single stranded (ss) DNA or ssRNA molecules of different origin to form a double stranded (ds) DNA, a dsRNA or a DNA-RNA duplex. Both nucleic acid strands must bear some sequence similarity in order to form stable hybrids by complementary base pairing. The process can be induced in the test tube or, alternatively, used for detection and identification of complementary sequences in ex vivosamples....