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Juvenile Ankylosing Spondylitis

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Textbook of Clinical Pediatrics

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Definition

The term juvenile-onset ankylosing spondylitis (AS) refers to a disease, which onset of symptoms occurs before the age of 16 years and its main features are familial aggregation, strong association with HLA-B27, as well as peripheral arthritis and enthesitis at onset and sacroiliitis and spondylitis throughout the course of the disease. Juvenile-onset AS is the counterpart of adult-onset AS, the prototype of the group of disease and syndromes known as spondyloarthritis (SpA). Either in children or adults, the SpA group includes undifferentiated forms, psoriatic arthritis (PsA), reactive arthritis (ReA), ulcerative colitis, and Chron’s disease.

Diagnosis

Juvenile-onset AS is diagnosed according to the modified New York criteria for AS (Table 155.1 ). The fulfillment of such criteria requires clinical and radiographic evidence of spinal and sacroiliac joint involvement, particularly structural radiographic changes of the sacroiliac joints. (Fig. 155.1 ). Since AS in children...

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Authors and Affiliations

  1. Department of Rheumatology, Hospital General de México Universidad Nacional Autónoma de México, Dr. Balmis 148, México, DF 06720, Mexico

    Dr. Rubén Burgos-Vargas M.D. (Professor)

  2. Department of Rheumatology, Hospital General de México, Dr. Balmis 148, México DF, 06720, México

    Dr. Rubén Burgos-Vargas M.D. (Professor) & Dr. Raúl Gutiérrez-Suárez M.D., MSc (Faculty of Medicine)

Authors
  1. Dr. Rubén Burgos-Vargas M.D.
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  2. Dr. Raúl Gutiérrez-Suárez M.D., MSc
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Correspondence to Rubén Burgos-Vargas M.D. .

Editor information

Editors and Affiliations

  1. Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia

    Abdelaziz Y. Elzouki (Professor of Pediatrics) (Professor of Pediatrics)

  2. National Center of Allergy, Asthma & Immunology (NCAAI), Riyadh, Saudi Arabia

    Harb A. Harfi (Director) (Director)

  3. Consultant Pediatric Gastroenterology & Hepatology, Islamic Hospital, Amman, Jordan

    Hisham M. Nazer

  4. Seattle Children's Hospital University of Washington, School of Medicine, Seattle, WA, USA

    F. Bruder Stapleton (Professor and Chair Department of Pediatrics) (Professor and Chair Department of Pediatrics)

  5. Alpert Medical School of Brown University, Woman and Infants Hospital, Providence, RI, USA

    William Oh (Professor of Pediatrics) (Professor of Pediatrics)

  6. University of Alabama, Birmingham, AL, USA

    Richard J. Whitley (Professor of Pediatrics) (Professor of Pediatrics)

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Burgos-Vargas, R., Gutiérrez-Suárez, R. (2012). Juvenile Ankylosing Spondylitis. In: Elzouki, A.Y., Harfi, H.A., Nazer, H.M., Stapleton, F.B., Oh, W., Whitley, R.J. (eds) Textbook of Clinical Pediatrics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-02202-9_155

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  • DOI: https://doi.org/10.1007/978-3-642-02202-9_155

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  • Print ISBN: 978-3-642-02201-2

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