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Detergents

  • Lilla LandeckEmail author
  • Lynn A. Baden
  • Swen-Malte John

Abstract

Household, personal, and industrial products contain detergents which play an important role in everyday life.

The term “detergency” is used to describe the process of cleaning by a surface-active agent (surfactant).

The most important ingredients of detergents are surfactants which display surface-tension-lowering properties so water can expand to wet surface, increasing washing effectiveness. Chemically, surfactants are amphiphilic molecules with a lipophilic tail and a hydrophilic head. They are categorized into four primary groups according to the charge present in the hydrophilic head: anionic, cationic, amphoteric, and nonionic. In the current market of cleaners and cleansers, anionic surfactants are the most common ones.

Surfactants may be irritating to the skin. The order of irritant potential of surfactants is the following: cationic = anionic > amphoteric > nonionic; however, mixtures of surfactants may elicit unexpected reactions.

Considering the widespread use and applications of household and personal detergents, the frequency of side effects to the skin is relatively low in an occupational as well in a personal exposure.

Keywords

Cationic Surfactant Anionic Surfactant Sodium Lauryl Sulfate Laundry Detergent Benzalkonium Chloride 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Abbas S, Goldberg JW, Massaro M (2004) Personal cleanser technology and clinical performance. Dermatol Ther Suppl 1:35–42CrossRefGoogle Scholar
  2. Andersen PH, Bindslev-Jensen C, Mosbech H, Zachariae H, Andersen KE (1998) Skin symptoms in patients with atopic dermatitis using enzyme-containing detergents. A placebo-controlled study. Acta Derm Venereol 78:60–2PubMedCrossRefGoogle Scholar
  3. Ananthapadmanabhan KP, Moore DJ, Subramanyan K, Misra M, Meyer F (2004) Cleansing without compromise: the impact of cleansers on the skin barrier and the technology of mild cleansing. Dermatol Ther Suppl 1:16–25CrossRefGoogle Scholar
  4. Austoria AJ, Lakshmi C, Srinivas CR, Anand CV, Mathew AC (2010) Irritancy potential of 17 detergents used commonly by the Indian household. Indian J Dermatol Venereol Leprol 76:249–53PubMedCrossRefGoogle Scholar
  5. Bajpai D, Tyagi VK (2007) Laundry detergents: an overview. J Oleo Sci 56:327–40PubMedCrossRefGoogle Scholar
  6. Basketter DA, English JS, Wakelin SH, White IR (2008) Enzymes, detergents and skin: facts and fantasies. Br J Dermatol 158:1177–81PubMedCrossRefGoogle Scholar
  7. Basketter DA, Pons-Guiraud A, van Asten A, Laverdet C, Marty JP, Martin L, Berthod D, Siest S, Giordano-Labadie F, Tennstedt D, Baeck M, Vigan M, Lainé G, Le Coz CJ, Jacobs MC, Bayrou O, Germaux MA (2010) Fragrance allergy: assessing the safety of washed fabrics. Contact Dermatitis 62:349–54PubMedCrossRefGoogle Scholar
  8. Belsito DV, Fransway AF, Fowler JF Jr, Sherertz EF, Maibach HI, Mark JG Jr, Mathias CG, Rietschel RL, Storrs FJ, Nethercott JR (2002) Allergic contact dermatitis to detergents: a multicenter study to assess prevalence. J Am Acad Dermatol 46:200–6PubMedCrossRefGoogle Scholar
  9. Corazza M, Lauriola MM, Zappaterra M, Bianchi A, Virgili A (2010) Surfactants, skin cleansing protagonists. J Eur Acad Dermatol Venereol 24:1–6PubMedCrossRefGoogle Scholar
  10. Corea NV, Basketter DA, Clapp C, Van Asten A, Marty JP, Pons-Guiraud A, Laverdet C (2006) Fragrance allergy: assessing the risk from washed fabrics. Contact Dermatitis 55:48–53PubMedCrossRefGoogle Scholar
  11. Ertel K (2000) Modern skin cleansers. Dermatol Clin 18:561–75PubMedCrossRefGoogle Scholar
  12. Effendy I, Maibach HI (1995) Surfactants and experimental irritant contact dermatitis. Contact Dermatitis 33:217–25PubMedCrossRefGoogle Scholar
  13. European Commission (1999) Scientific committee on cosmetic products and non-food products intended for consumers. Opinion concerning fragrance allergy in consumers. http://ec.europa.eu/health/ph_risk/committees/sccp/documents/out98_en.pdf. Accessed 12 Dec 2010
  14. Fartasch M, Diepgen TL, Drexler H, Elsner P, Fluhr JW, John SM, Kresken J, Wigger-Alberti W (2011) Berufliche Hautmittel. http://www.derma.de/fileadmin/derma/pdfs/ll_berufliche_hautmittel.pdf. Accessed Feb 2011
  15. Fluhr JW, Elias PM (2002) Stratum corneum pH: formation and function of the acid mantle. Exog Dermatol 1:163–75CrossRefGoogle Scholar
  16. Fowler JF Jr (2004) Cocamidopropyl betaineb. Dermatitis 15:3–4PubMedCrossRefGoogle Scholar
  17. Lodén M, Buraczewska I, Edlund F (2003) The irritation potential and reservoir effect of mild soaps. Contact Dermatitis 49:91–6PubMedCrossRefGoogle Scholar
  18. Löffler H, Happle R (2003) Profile of irritant patch testing with detergents: sodium lauryl sulfate, sodium laureth sulfate and alkyl polyglucoside. Contact Dermatitis 48(2):6–32Google Scholar
  19. Magnano M, Silvani S, Vincenzi C, Nino M, Tosti A (2009) Contact allergens and irritants in household washing and cleaning products. Contact Dermatitis 61:337–41PubMedCrossRefGoogle Scholar
  20. Matthies W, Löhr A, Ippen H (1990) Importance of detergent residues from the dermatoxicological point of view. Derm Beruf Umwelt 36:184–9Google Scholar
  21. Pepys J, Mitchell J, Hawkins R, Malo JL (1985) A longitudinal study of possible allergy to enzyme detergents. Clin Allergy 15:101–15PubMedCrossRefGoogle Scholar
  22. Regulation (EC) No 648/2004 of the European Parliament and of the Council of 31 March 2004 on detergents. http://eurlex.europa.eu/smartapi/cgi/sga_doc?smartapi!celexapi!prod!CELEXnumdoc&lg=EN&numdoc=32004R0648&model=guichett. Accessed 12 Dec 2010
  23. Schweigert MK, Mackenzie DP, Sarlo K (2000) Occupational asthma and allergy associated with the use of enzymes in the detergent industry–a review of the epidemiology, toxicology and methods of prevention. Clin Exp Allergy 30:1511–8PubMedCrossRefGoogle Scholar
  24. Terhaer FK, Bock M, Fartasch M, Gabard B, Elsner P, Kleesz P, Landeck L, Pohrt U, Seyfarth F, Schliemann S, Diepgen TL, Zagrodnik F, John SM (2010) Safety, effectiveness and comparability of professional skin cleansers. J Dtsch Dermatol Ges 8:806–10PubMedGoogle Scholar
  25. The Council of the European Communities: Council Directive 76/768/EEC of 27 July 1976 on the approximation of the laws of the Member States relating to cosmetic products. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=CELEX:31976L0768:EN:HTML. Accessed 21 Dec 2010
  26. The Soap and Detergent Association of Canada (2010) http://www.healthycleaning101.org/english/SDAC_soaps.html#his. Accessed 21 Dec 2010
  27. Wagner G (2010) Waschmittel. Wiley-VCH, WeinheimCrossRefGoogle Scholar
  28. White IR, Lewis J, El Alami A (1985) Possible adverse reactions to an enzyme-containing washing powder. Contact Dermatitis 13:175–9PubMedCrossRefGoogle Scholar
  29. Yazar K, Johnsson S, Lind ML, Boman A, Lidén C (2011) Preservatives and fragrances in selected consumer-available cosmetics and detergents. Contact Dermatitis 64:265–72Google Scholar
  30. Zug KA, Warshaw EM, Fowler JF Jr, Maibach HI, Belsito DL, Pratt MD, Sasseville D, Storrs FJ, Taylor JS, Mathias CG, Deleo VA, Rietschel RL, Marks J (2009) Patch-test results of the North American Contact Dermatitis Group 2005–2006. Dermatitis 20:149–60PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Lilla Landeck
    • 1
    Email author
  • Lynn A. Baden
    • 2
  • Swen-Malte John
    • 3
  1. 1.Department of Dermatology, Environmental Medicine, Health TheoryUniversity of OsnabrueckOsnabrueckFederal Republic of Germany
  2. 2.Centre Dermatology and Aesthetic MedicineNewtonUSA
  3. 3.Department of Dermatology, Environmental Medicine and Health TheoryUniversity of OsnabrueckOsnabrueckGermany

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