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Post-neurosurgical meningitis is an inflammation of the coverings of the brain following cranial procedures like craniotomy, stereotactic biopsy, and stereotactic craniotomy or ventriculoperitoneal shunt placement.
Besides the superficial SSI, post-neurosurgical meningitis is the second most common CNS infection after craniotomy. Post-neurosurgical meningitis occurs in 1–6% of cranial procedures.
Risk factors for postoperative meningitis are concomitant incision infection, cerebrospinal fluid (CSF) leakage, duration of surgery, emergency surgery, and early reoperation. Also EVD and intraventricular shunting increase the risk of post-neurosurgical meningitis (see also External Ventricular Drainage (EVD) Related CNS Infection and Shunt-Related CNS Infection).
Pathogens causing post-neurosurgical meningitis are mainly staphylococci (Staphylococcus aureus, coagulase negative staphylococci (CoNS)), gram-negative bacilli (Esch...