Encyclopedia of Intensive Care Medicine

2012 Edition
| Editors: Jean-Louis Vincent, Jesse B. Hall

Venous Oxygen Saturation, Central and Mixed

Reference work entry
DOI: https://doi.org/10.1007/978-3-642-00418-6_220

Synonyms

Definition

Mixed venous oxygen saturation is the oxygen saturation measured in the blood taken from the pulmonary artery. In general, a pulmonary artery catheter is necessary to measure SvO2. The term “mixed” refers to the fact that the pulmonary artery carries the venous blood from the whole body as a mix of the blood from the inferior and superior vena cava. In contrast, the central venous oxygen saturation is measured in the blood taken from the superior vena cava usually via a central venous catheter, thus, reflecting venous blood from the upper body only.

Pre-existing Condition

Venous oximetry is applied to monitor the adequacy of tissue oxygenation. This indication is derived from the Fick principle, where O2 consumption is equal to the product of cardiac output and the arteriovenous O2 content difference. When the equation is solved for SvO2, this parameter is...

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References

  1. 1.
    Bloos F, Reinhart K (2005) Venous oximetry. Intensive Care Med 31(7):911–913PubMedGoogle Scholar
  2. 2.
    Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B et al (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock. New Engl J Med 345(19):1368–1377PubMedGoogle Scholar
  3. 3.
    Donati A, Loggi S, Preiser J, Orsetti G, Münch C, Gabbanelli V et al (2007) Goal-directed intraoperative therapy reduces morbidity and length of hospital stay in high-risk surgical patients. Chest 132(6):1817–1824PubMedGoogle Scholar
  4. 4.
    Polonen P, Ruokonen E, Hippelainen M, Poyhonen M, Takala J (2000) A prospective, randomized study of goal-oriented hemodynamic therapy in cardiac surgical patients. Anesth Analg 90(5):1052–1059PubMedGoogle Scholar
  5. 5.
    Dueck MH, Klimek M, Appenrodt S, Weigand C, Boerner U (2005) Trends but not individual values of central venous oxygen saturation agree with mixed venous oxygen saturation during varying hemodynamic conditions. Anesthesiology 103(2):249–257PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  1. 1.Department of Anesthesiology and Intensive Care MedicineJena University HospitalJenaGermany