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Textbook of Aging Skin pp 799–809Cite as

The Potential of Probiotics and Prebiotics for Skin Health

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Abstract

Microbes are ubiquitous in the environment, and despite last century’s improvement in hygiene, human beings are continuously exposed to them. In fact, humans are not only exposed to microbes, but also hosting them. An adult human being consists of an estimated 1013 eukaryotic cells. At the same time, human body hosts an estimated 1014 microbes, most of them are in the large intestine but also appreciable amounts on the various sites of the skin. The composition of this microbiota (formerly known as “microflora”) is complex and influenced by various environmental factors. It is, therefore, not surprising that different parts of the human body, which are exposed to the outside environment, will have a different microbiota. The composition and activity of the skin microbiota will be discussed in more detail below.

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References

  1. Guidelines for the evaluation of probiotics in food. http://www.who.int/foodsafety/publications/fs_management/probiotics2/en/: 2002.

  2. Ouwehand AC, Mäkeläinen H, Tiihonen K, Rautonen N. Digestive health. In: Mitchell H (ed) Sweeteners and Sugar Alternatives in Food Technology. Oxford: Blackwell, 2006, pp. 44–53.

    Chapter  Google Scholar 

  3. Warskulat U, Flogel U, Jacoby C, Hartwig HG, Thewissen M, Merx MW, et al. Taurine transporter knockout depletes muscle taurine levels and results in severe skeletal muscle impairment but leaves cardiac function uncompromised. FASEB J. 2004;18(3):577–579.

    CAS  PubMed  Google Scholar 

  4. Gao Z, Tseng CH, Pei Z, Blaser MJ. Molecular analysis of human forearm superficial skin bacterial biota. Proc Natl Acad Sci USA. 2007;104(8):2927–2932.

    Article  CAS  PubMed  Google Scholar 

  5. Grice EA, Kong HH, Renaud G, Young AC, Bouffard GG, Blakesley RW, et al. A diversity profile of the human skin microbiota. Genome Res. 2008;18(7):1043–1050.

    Article  CAS  PubMed  Google Scholar 

  6. Gao Z, Tseng CH, Strober BE, Pei Z, Blaser MJ. Substantial alterations of the cutaneous bacterial biota in psoriatic lesions. PLoS ONE. 2008;3(7):e2719.

    Article  PubMed  Google Scholar 

  7. Paulino LC, Tseng CH, Strober BE, Blaser MJ. Molecular analysis of fungal microbiota in samples from healthy human skin and psoriatic lesions. J Clin Microbiol. 2006;44(8):2933–2941.

    Article  CAS  PubMed  Google Scholar 

  8. Dekio I, Hayashi H, Sakamoto M, Kitahara M, Nishikawa T, Suematsu M, et al. Detection of potentially novel bacterial components of the human skin microbiota using culture-independent molecular profiling. J Med Microbiol. 2005;54(Pt 12):1231–1238.

    Article  CAS  PubMed  Google Scholar 

  9. Bek-Thomsen M, Lomholt HB, Kilian M. Acne is not associated with yet-uncultured bacteria. J Clin Microbiol. 2008;46(10):3355–3360.

    Article  CAS  PubMed  Google Scholar 

  10. Dekio I, Sakamoto M, Hayashi H, Amagai M, Suematsu M, Benno Y. Characterization of skin microbiota in patients with atopic dermatitis and in normal subjects using 16S rRNA gene-based comprehensive analysis. J Med Microbiol. 2007;56(Pt 12):1675–1683.

    Article  CAS  PubMed  Google Scholar 

  11. Cinque B, Di Marzio L, Della Riccia DN, Bizzini F, Giuliani M, Fanini D, et al. Effect of Bifidobacterium infantis on Interferon- gamma- induced keratinocyte apoptosis: a potential therapeutic approach to skin immune abnormalities. Int J Immunopathol Pharmacol. 2006;19(4):775–786.

    CAS  PubMed  Google Scholar 

  12. Ouwehand A, Lahtinen S, Nurminen P. Lactobacillus rhamnosus HN001 and Bifidobacterium lactis HN019. In: Lee YK, Salminen S (eds) Handbook of Probiotics and Prebiotics. Hoboken: Wiley, 2009, pp. 473–477.

    Google Scholar 

  13. Lee J, Seto D, Bielory L. Meta-analysis of clinical trials of probiotics for prevention and treatment of pediatric atopic dermatitis. J Allergy Clin Immunol. 2008;121(1):116–121.

    Article  PubMed  Google Scholar 

  14. Chapat L, Chemin K, Dubois B, Bourdet-Sicard R, Kaiserlian D. Lactobacillus casei reduces CD8+ T cell-mediated skin inflammation. Eur J Immunol. 2004;34(9):2520–2528.

    Article  CAS  PubMed  Google Scholar 

  15. Watanabe J, Sasajima N, Aramaki A, Sonoyama K. Consumption of fructo-oligosaccharide reduces 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice. Br J Nutr. 2008;100(2):339–346.

    Article  CAS  PubMed  Google Scholar 

  16. Peguet-Navarro J, Dezutter-Dambuyant C, Buetler T, Leclaire J, Smola H, Blum S. et al. Supplementation with oral probiotic bacteria protects human cutaneous immune homeostasis after UV exposure-double blind, randomized, placebo controlled clinical trial. Eur J Dermatol. 2008;18(5):504–511.

    CAS  PubMed  Google Scholar 

  17. Baba H, Masuyama A, Takano T. Effects of Lactobacillus helveticus-fermented milk on the differentiation of cultured normal human epidermal keratinocytes. J Dairy Sci. 2006;89(6):2072–2075.

    Article  CAS  PubMed  Google Scholar 

  18. Miyazaki K, Hanamizu T, Iizuka R, Chiba K. Bifidobacterium-fermented soy milk extract stimulates hyaluronic acid production in human skin cells and hairless mouse skin. Skin Pharmacol Appl Skin Physiol. 2003;16(2):108–116.

    CAS  PubMed  Google Scholar 

  19. Ouwehand AC, Salminen S. The health effects of cultured milk products with viable and non-viable bacteria. Int Dairy J. 1998;8:749–758.

    Article  Google Scholar 

  20. Valdez JC, Peral MC, Rachid M, Santana M, Perdigon G. Interference of Lactobacillus plantarum with Pseudomonas aeruginosa in vitro and in infected burns: the potential use of probiotics in wound treatment. Clin Microbiol Infect. 2005;11(6):472–479.

    Article  CAS  PubMed  Google Scholar 

  21. Rodrigues KL, Caputo LR, Carvalho JC, Evangelista J, Schneedorf JM. Antimicrobial and healing activity of kefir and kefiran extract. Int J Antimicrob Agents. 2005;25(5):404–408.

    Article  CAS  PubMed  Google Scholar 

  22. Nikitenko VI. Infection prophylaxis of gunshot wounds using probiotics. J Wound Care. 2004;13(9):363–366.

    CAS  PubMed  Google Scholar 

  23. Lee J, Seto D, Bielory L. Meta-analysis of clinical trials of probiotics for prevention and treatment of pediatric atopic dermatitis. J Allergy Clin Immunol. 2008;121(1):116–121.

    Article  PubMed  Google Scholar 

  24. Kalliomäki M, Salminen S, Arvilommi H, Kero P, Koskinen P, Isolauri E.2001; Probiotics in primary prevention of atopic disease: a randomized placebo-controlled trial. Lancet. 357:1076–1079.

    Article  PubMed  Google Scholar 

  25. Kopp MV, Hennemuth I, Heinzmann A, Urabanek R. Randomized, double-blind, placebo-controlled trial of probiotics for primary prevention: no clinical effects of Lactobacillus GG supplementation. Pediatrics. 2008;121(4):850–856.

    Article  Google Scholar 

  26. Kukkonen K, Savilahti E, Haahtela T, Juntunen-Backman K, Korpela R, Poussa T, Tuure T, Kuitunen M. Probiotics and prebiotic galacto-oligosaccharides in th eprevebtion of allergic diseases: A randomized, double-blind, placebo-controlled trail. J Allergy Clin Immunol. 2007;119(1):192–198.

    Article  CAS  PubMed  Google Scholar 

  27. Abrahamsson TR, Jakobsson T, Bottcher MF, Fredrikson M, Jenmalm MC, Bjorksten B, Oldaeus G. Probiotics in prevention of IgE-associated eczema: a double-blind, randomized, placebo-controlled trail. J Allergy Clin Immunol. 2007;119(5):1174–1180.

    Google Scholar 

  28. Taylor AL, Dunstan JA, Prescott SL. Probiotic supplementation for the first 6 months of life fails to reduce the risk of atopic dermatitis and increases the risk of allergen sensitization in high-risk children: a randomized controlled trail. J Allergy Clin Immunol. 2007;119(1):184–191.

    Article  PubMed  Google Scholar 

  29. Wickens K, Black PN, Stanley TV, Mitchell, Fitzharris P, Tannock GW, Purdie G, Crane J. A differential effect of 2 probiotics in the prevention of eczema and atopy: a double-blind, randomized, placebo-controlled trail. J Allergy Clin Immunol. 2008;122(4):788–794.

    Article  PubMed  Google Scholar 

  30. Lodinová-Zádniková R, Cukrowska B, Tlaskalová-Hogenová H. Oral administration of probiotic Escherichia coli after birth reduces frequency of allergies and repeated infections later in life (after 10 and 20 years). Int Arch Allergy Immunol. 2003;131:209–211.

    Article  PubMed  Google Scholar 

  31. Moro G, Arslanoglu S, Stahl B, Jelinek J, Wahn U, Boehm G. A mixture of prebiotic oligasaccharides reduces the incidence of atopic dermatitis during the first six months of age. Arch Dis Child. 2006; 91(10):814–819

    Article  CAS  PubMed  Google Scholar 

  32. Isolauri E, Arvola T, Sütas Y, Moilanen E, Salminen S. Probiotics in the management of atopic eczema. Clin Exp Allergy. 2000;30:1604–1610.

    Article  CAS  PubMed  Google Scholar 

  33. Brouwer ML, Wolt-plompen SA, Dubois AE, van der HS, Jansen DF, Hoijer MA, et al. No effects of probiotics on atopic dermatitis in infancy: a randomized placebo-controlled trail. Clin Exp Allergy. 2006;36(7):899–906.

    Article  CAS  PubMed  Google Scholar 

  34. Fölster-Holst R, Muller F, Schnopp N, abeck D, Kreiselmaier I, Lenz T, von Rüden U, Schrezenmeir J, Christophers E, Weichenthal M. Prospective, randomized controlled trial on Lactobacillus rhamnosus in infants with moderate to severe atopic dermatitis. Br J Dermatol. 2006;155(6):1256–1261.

    Article  PubMed  Google Scholar 

  35. Viljanen M, Savilahti E, Hahtela T, Juntunen-Backman K, Korpela R, Poussa T, Tuure T, Kuitunen M. Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: a double blind placebo-controlled trial. Allergy. 2005;60(4):494–500.

    Article  CAS  PubMed  Google Scholar 

  36. Rosenfeldt V, Benfeldt E, Nielsen SD, Michaelsen KF, Jeppensen DL, Valerius NH, Paerregaard A. Effect of probiotic Lactobacillus strains in children with atopic dermatitis. J Allergy Clin Immunol. 2003;111(2):389–395.

    Article  PubMed  Google Scholar 

  37. Sistek D, Kelly R, Wickens K, Stanley T, Fitzharris P, Crane J. Is the effect of probiotics on atopic dermatitis confined to food sensitized children? Clin Exp Allergy. 2006;36(5):629–633.

    Article  CAS  PubMed  Google Scholar 

  38. Weston S, Halbert A, Richmond P, Prescott SL. Effects of probiotics on atopic dermatitis: a randomized controlled trial. Arch Dis Child. 2005;90(9):892–897.

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Health and Nutrition, Danisco, FIN-02460, Kantvik, Finland

    Arthur C. Ouwehand, Kirsti Tiihonen & Sampo Lahtinen

Authors
  1. Arthur C. Ouwehand
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  2. Kirsti Tiihonen
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  3. Sampo Lahtinen
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Editor information

Editors and Affiliations

  1. The Procter & Gamble Company, 6110 Center Hill Avenue, 45224, Cincinnati, OH, USA

    Miranda A. Farage Ph.D. (Principal Scientist) (Principal Scientist)

  2. The Procter & Gamble Company, 6110 Center Hill Avenue, 45224, Cincinnati, OH, USA

    Kenneth W. Miller Ph.D. (Associate Director) (Associate Director)

  3. Department of Dermatology, University of California, School of Medicine, 222 SE 8th Ave., Suite 563, 94122, San Francisco, CA, USA

    Howard I. Maibach M.D. (Professor) (Professor)

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© 2010 Springer-Verlag Berlin Heidelberg

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Ouwehand, A.C., Tiihonen, K., Lahtinen, S. (2010). The Potential of Probiotics and Prebiotics for Skin Health. In: Farage, M.A., Miller, K.W., Maibach, H.I. (eds) Textbook of Aging Skin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-89656-2_77

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  • DOI: https://doi.org/10.1007/978-3-540-89656-2_77

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-89655-5

  • Online ISBN: 978-3-540-89656-2

  • eBook Packages: MedicineReference Module Medicine

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