Well-defined area of retinal pigment epithelium (RPE), outer retinal layer, and choriocapillaris atrophy developing secondary to non-exudative age-related macular degeneration (AMD).
Retinal pighment epithelium (RPE) atrophy represents a downstream pathogenetic pathway in various retinal diseases (see “Differential Diagnosis”). In the elderly, it is most frequently associated with non-exudative AMD and it then terment geographic atrophy (GA). While various pathways may be involved, the precise pathogenesis in the context of AMD is yet unclear.
- Holz FG, Pauleikhoff D, Spaide RF, Bird AC (eds) (2013) Age-related macular degeneration, 2nd edn. Springer, Berlin, pp 125–132, 167Google Scholar