Encyclopedia of Psychopharmacology

2010 Edition
| Editors: Ian P. Stolerman

Forward Genetics/Reverse Genetics

  • Etienne Sibille
  • Nicole Edgar
Reference work entry
DOI: https://doi.org/10.1007/978-3-540-68706-1_635

Synonyms

Definition

Forward genetics is the examination of the genetic cause of an altered or abnormal phenotype introduced by a chemical mutagenesis or mutation by irradiation (e.g., phenotype → genotype). In reverse genetics, a particular gene is altered and the phenotype is investigated (e.g., genotype → phenotype).

Cross-References

Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Etienne Sibille
    • 1
  • Nicole Edgar
    • 2
  1. 1.Center for Neuroscience, Department of PsychiatryUniversity of PittsburghPittsburghUSA
  2. 2.Center for Neuroscience, Department of PsychiatryUniversity of PittsburghPittsburghUSA