Encyclopedia of Psychopharmacology

Editors: Ian P. Stolerman

Quazepam

  • Britta Hahn
Reference work entry
DOI: https://doi.org/10.1007/978-3-540-68706-1_1717

Definition

Quazepam is a benzodiazepine with hypnotic and anticonvulsant properties. Clinically, quazepam is particularly effective in the short-term treatment of insomnia by inducing and maintaining sleep. Unlike other benzodiazepines, quazepam selectively targets GABAA type 1 receptors, but one of its major long-acting metabolites does not share this selectivity. Due to its long-lasting action, impairment of motor function is a significant side effect. Quazepam use is subject to tolerance, abuse, dependence, and withdrawal, although possibly with reduced severity as compared with other benzodiazepines.

Cross-References

Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Britta Hahn
    • 1
  1. 1.Maryland Psychiatric Research CenterUniversity of Maryland School of MedicineBaltimoreUSA