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First-order elimination kinetics depends on the concentration of only one reactant (drug) and a constant fraction of the drug in the body is eliminated per unit time. The rate of elimination is proportional to the amount of drug in the body. The majority of drugs are eliminated in this way.
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© 2010 Springer-Verlag Berlin Heidelberg
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Wolff, K. (2010). First-Order Elimination Kinetics. In: Stolerman, I.P. (eds) Encyclopedia of Psychopharmacology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68706-1_1522
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DOI: https://doi.org/10.1007/978-3-540-68706-1_1522
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-68698-9
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