Encyclopedia of Psychopharmacology

2010 Edition
| Editors: Ian P. Stolerman

First-Order Elimination Kinetics

Reference work entry
DOI: https://doi.org/10.1007/978-3-540-68706-1_1522
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Synonyms

Kel

Definition

First-order elimination kinetics depends on the concentration of only one reactant (drug) and a constant fraction of the drug in the body is eliminated per unit time. The rate of elimination is proportional to the amount of drug in the body. The majority of drugs are eliminated in this way.

Cross-References

Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  1. 1.King’s College LondonInstitute of PsychiatryLondonUK