Encyclopedia of Cancer

2009 Edition
| Editors: Manfred Schwab

RGD

Reference work entry
DOI: https://doi.org/10.1007/978-3-540-47648-1_5090

Definition

A tripeptide Arg-Gly-Asp; Arganine-Glysine-Aspartic Acid is a recognition motif found in the amino acid sequence of many integrin-binding proteins. The RGD motif facilitates binding of many  Integrins, including α3β1, α4β1, α5β1, α8β1, α9β1, αvβ1, αIIbβ3, αvβ3, αvβ5, αvβ6, and α4β7.

 Integrin Signalling

 Osteopontin

 TAT Protein of HIV

Copyright information

© Springer-Verlag Berlin Heidelberg New York 2008