Encyclopedia of Cancer

2009 Edition
| Editors: Manfred Schwab

Metabolic Activation

Reference work entry
DOI: https://doi.org/10.1007/978-3-540-47648-1_3652

Definition

Bioconversion of unreactive procarcinogens to reactive electrophiles through the action of Phase I and Phase II drug metabolizing enzymes.

 Carcinogen Macromolecular Adducts

 Tobacco Carcinogenesis

Copyright information

© Springer-Verlag Berlin Heidelberg New York 2008