GABAA Receptors
Reference work entry
DOI: https://doi.org/10.1007/978-3-540-38918-7_5747
GABAA receptors are pentameric complexes on the postsynaptic membrane with a central pore with selectivity for chloride ions. Benzodiazepines and barbiturates increase the GABA-induced chloride currents, leading to hyperpolarization of the postsynaptic membrane.
Copyright information
© Springer-Verlag Berlin Heidelberg New York 2008