Furin, also known as paired basic amino‐acid‐cleaving enzyme (PACE), is a membrane bound subtilisin‐like serine protease of the trans Golgi compartment. It is ubiquitously expressed and mediates processing of many protein precursors at Arg‐X‐Lys/Arg‐Arg sites.

So far, seven mammalian precursor convertases (PCs) have been identified: furin, PC1, PC2, PC4, PC5, PACE4 and PC7.

 Somatostatin