Reference Work Entry

Encyclopedia of Molecular Pharmacology

pp 41-41

Adipose Tissue

The adipose organ consists of two distinct tissues – brown and white adipose tissue. Brown adipose tissue is specialised for thermoregulatory heat generation (thermogenesis) through the presence of the tissue‐specific mitochondrial uncoupling protein‐1 (UCP‐1); only limited amounts are present in most humans. White adipose tissue is the major fuel storage organ in mammals and birds, the key cell type (∼50% of total cell content) being the adipocytes which store large amounts of triacylglycerol; the other cell types are fibroblasts, preadipocytes, macrophages and endothelial cells.


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