Cholesterolosis, Gallbladder
A type of hyperplastic cholecystosis resulting from the accumulation of triglycerides within macrophages and cholesterol esters mainly in the submucosal layer or lamina propria of the gallbladder wall. A causal association with cholesterol gallstones, super saturation of bile with cholesterol, and hyperlipidemia remains unconfirmed. Two types have been described: a diffuse form, also named “strawberry” gallbladder, and a polypoid form. The gross appearance of strawberry gallbladder includes a diffuse thickening and the presence of yellowish, diffuse, granular, lipid deposits, varying in distribution and size, in the gallbladder mucosa that resemble a strawberry. The polypoid form is characterized by single or multiple, small, discrete polypoid excrescences composed of cholesterol‐filled macrophages.