Skip to main content

Glomerular Map

  • Reference work entry
  • First Online:
Encyclopedia of Neuroscience
  • 480 Accesses

Synonyms

Odotopic Representation; Chemotopic Representation; Glomerulus Map

Definition

The orderly and species-stereotypical projection of olfactory sensory neurons from the olfactory epithelium into glomeruli of the main olfactory bulb produces a glomerular map wherein individual consistently located glomeruli can be related to individual odorant receptor genes. Because odorant receptors are differentially activated by a characteristic set of odorant ligands, different odorants activate characteristic spatial patterns of activity in the glomerular layer of the olfactory bulb (odotopic representation). Because odorants that share particular aspects of chemical structure and/or overall molecular properties overlap in their stimulation of receptors and glomeruli, and because glomeruli responding to similar odorant chemicals tend to be located near one another in the bulb, the glomerular map can be described in terms of odorant chemistry (chemotopic representation). Similarities in the...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  1. Buck LB (1996) Information coding in the vertebrate olfactory system. Annu Rev Neurosci 19:517–544

    Article  CAS  PubMed  Google Scholar 

  2. Mombaerts P (2006) Axonal wiring in the mouse olfactory system. Annu Rev Cell Dev Biol 22:713–737

    Article  CAS  PubMed  Google Scholar 

  3. Schoenfeld TA, Cleland TA (2005) The anatomical logic of smell. Trends Neurosci 28:620–627

    Article  CAS  PubMed  Google Scholar 

  4. Johnson BA, Leon M (2007) Chemotopic odorant coding in a mammalian olfactory system. J Comp Neurol 503:1–34

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Xu F, Greer CA, Shepherd GM (2000) Odor maps in the olfactory bulb. J Comp Neurol 422:489–495

    Article  CAS  PubMed  Google Scholar 

  6. Mori K, Takahashi YK, Igarashi KM, Yamaguchi M (2006) Maps of odorant molecular features in the mammalian olfactory bulb. Physiol Rev 86:409–433

    Article  CAS  PubMed  Google Scholar 

  7. Johnson BA, Farahbod H, Xu Z, Saber S, Leon M (2004) Local and global chemotopic organization: general features of the glomerular representations of aliphatic odorants differing in carbon number. J Comp Neurol 480:234–249

    Article  CAS  PubMed  Google Scholar 

  8. Yokoi M, Mori K, Nakanishi S (1995) Refinement of odor molecule tuning by dendrodendritic synaptic inhibition in the olfactory bulb. Proc Natl Acad Sci USA 92:3371–3375

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Youngentob SL, Johnson BA, Leon M, Sheehe PR, Kent PF (2006) Predicting odorant quality perceptions from multidimensional scaling of olfactory bulb glomerular activity patterns. Behav Neurosci 120:1337–1345

    Article  PubMed  PubMed Central  Google Scholar 

  10. Cleland TA, Johnson BA, Leon M, Linster C (2007) Relational representation in the olfactory system. Proc Natl Acad Sci USA 104:1953–1958

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Springer-Verlag GmbH Berlin Heidelberg

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Johnson, B.A., Leon, M. (2009). Glomerular Map. In: Binder, M.D., Hirokawa, N., Windhorst, U. (eds) Encyclopedia of Neuroscience. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-29678-2_2024

Download citation

Publish with us

Policies and ethics