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Pancreatic Neuroendocrine Tumors

  • Thiruvengadam MunirajEmail author
  • Harry R. Aslanian
Living reference work entry
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Abstract

Neuroendocrine tumors (NETs) are a relatively rare and heterogeneous group, comprising about 2% of all malignancies with almost 2/3 of NETs being nonfunctional tumors. The incidence increases with age. Most non-appendix, non-pancreas NETs are seen in age over 60 years. Diagnosis of NET is often challenging and requires careful clinical history along with laboratory tests and an array of imaging procedures. While functioning NETs could present with symptoms related to hormone hypersecretion, non-functioning NETs often present incidentally or due to mass effect. Surgical resection remains the treatment of choice even with metastatic disease. The newer diagnostic and treatment modalities offer potential treatment and prolong disease-free survival for patients with improvement in quality of life.

Keywords

Pancreatic Neuroendocrine Cancer Staging Confocal Endoscopic ultrasound Octreoscan MEN Neuroendocrine tumors and management 

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Authors and Affiliations

  1. 1.Yale University School of MedicineNew HavenUSA

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