Enzyme-Responsive Hydrogels

  • Shah M. Reduwan BillahEmail author
  • Md. Ibrahim H. Mondal
  • Sazzad H. Somoal
  • M. Nahid Pervez
  • Md. Obidul Haque
Living reference work entry
Part of the Polymers and Polymeric Composites: A Reference Series book series (POPOC)


In an enzymatically responsive system, a suitable enzyme is used as a stimulus for a control release or delivery at a specifically targeted site where that enzyme is designed in such a way that can work at certain controlled conditions (such as temperature, pH). Enzyme-responsive hydrogels prepared from cellulose along with other materials have suitable macromolecular networks and can work in controlled environment. Specifically designed enzymatic stimuli-responsive system, one of the highly explored techniques, popularly explored to add a triggerable agent (such as a polymer or a lipid) that can encapsulate the active component in a protective manner. Usually, this active agent is responsive to degradation or swelling when it reaches at the target site. An enzymatic stimulus-responsive system is highly attractive field of research due to its many potential applications (e.g., in controlled release, drug delivery, and other areas of life and material sciences). This chapter gives a brief overview on the design and uses of enzyme-responsive hydrogels based on cellulose and other polymers for their various applications in different fields including in controlled drug delivery and other areas of biomedical and material sciences.


Cellulose Hydrogels Enzyme Enzyme-responsive hydrogels Stimuli-responsive hydrogels Drug delivery Biomedical 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Shah M. Reduwan Billah
    • 1
    • 2
    • 3
    Email author
  • Md. Ibrahim H. Mondal
    • 4
  • Sazzad H. Somoal
    • 5
  • M. Nahid Pervez
    • 3
  • Md. Obidul Haque
    • 4
  1. 1.CCIRA UK LimitedGalashielsUK
  2. 2.Department of ChemistryDurham UniversityDurhamUK
  3. 3.School of Textiles and DesignHeriot-Watt University, Scottish Borders CampusGalashielsUK
  4. 4.Polymer and Textiles Research Lab, Department of Applied Chemistry and Chemical EngineeringRajshahi UniversityRajshahiBangladesh
  5. 5.Institute for Environmental SciencesUniversity of Koblenz-LandauLandauGermany

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