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Synthetic Hydrogels and Their Impact on Health and Environment

  • Ljubiša B. Nikolić
  • Aleksandar S. Zdravković
  • Vesna D. Nikolić
  • Snežana S. Ilić-Stojanović
Living reference work entry
Part of the Polymers and Polymeric Composites: A Reference Series book series (POPOC)

Abstract

Hydrogels have been discovered nearly 60 years ago and due to their permeability to water systems, they have become very important materials for use in comparison to other polymers. Hydrogels are materials first rationally designed for use in human medicine, and they find important usage in various areas, for example, in products for personal care, pharmaceutical, agriculture, and environmental protection. Especially interesting is the class of stimuli-sensitive hydrogels, due to their properties to respond to changes in pH, temperature, and ionic strength of the surrounding medium, whereby changes exist in the network structure, for example, swelling properties. Hydrogels have significant applications: in diagnosis, as substrates or implants in tissue engineering, as drug delivery carriers, and in cosmetics. Water pollution by heavy metals and dyes is a major environmental problem because of toxicity to the living world, bioaccumulation, and bio-non-degradability. Adsorption of heavy metals, radioactive elements, and dyes using the hydrogels is an effective way for their removal. The mechanism of heavy metals and dye ions removal using hydrogels could be explained by the physical adsorption, hydrogen bonding, complexation, and/or chelation and ion exchange. The pollutants adsorption process using hydrogels has some important advantages compared to conventional techniques: high adsorption capacity for removal of pollutants from aqueous solutions, binding ability, and reusability (regeneration). Hydrogels have applications in some systems for the controlled and sustained release of pesticides and fertilizers, so reducing the contamination of the soil and surface water by these agrochemicals.

Keywords

Hydrogel Synthesis Controlled/modified release Drug carrier Adsorption Pollutants 

Notes

Acknowledgments

Financial support provided by the Ministry of Education, Science and Technological Development of the Republic of Serbia (projects No. TR 34012) is gratefully acknowledged.

References

  1. 1.
    Ratner BD, Hoffman AS (1976) Synthetic hydrogels for biomedical applications. In: Andrade JD (ed) Hydrogels for medical and related applications, vol 31. American Chemical Society, Washington, DC, pp 1–36CrossRefGoogle Scholar
  2. 2.
    Peppas NA (1986) Hydrogels of poly(vinyl alcohol) and its copolymers. In: Peppas NA (ed) Hydrogels in medicine and pharmacy, vol 2. CRC Press, Boca Raton, pp 1–48Google Scholar
  3. 3.
    Peppas NA (1991) Physiologically responsive hydrogels. J Bioact Compat Polym 6(3):241–246CrossRefGoogle Scholar
  4. 4.
    Ilić-Stojanović SS, Nikolić LB, Nikolić VD, Petrović SD (2016) Smart hydrogels for pharmaceutical applications. In: Keservani RK, Sharma AK, Kesharwani RK (eds) Novel approaches for drug delivery. IGI Global, Hershey, pp 278–310Google Scholar
  5. 5.
    Grant R, Grant C (1987) Grant & Hackh’s chemical dictionary, 5th edn. McGraw-Hill, New York, pp 1–641Google Scholar
  6. 6.
    Corkhill PH, Jolly AM, Ng CO, Tighe BJ (1987) Synthetic hydrogels: 1. Hydroxyalkyl acrylate and methacrylate copolymers-water binding studies. Polymer 28(10):1758–1766CrossRefGoogle Scholar
  7. 7.
    Amin MCIM, Ahmad N, Halib N, Ahmad I (2012) Synthesis and characterization of thermo- and pH-responsive bacterial cellulose/acrylic acid hydrogels for drug delivery. Carbohydr Polym 88(2):465–473CrossRefGoogle Scholar
  8. 8.
    Fei C, Huang D, Feng S (2012) Adsorption behavior of amphoteric double-network hydrogel based on poly(acrylic acid) and silica gel. J Polym Res 19:9929CrossRefGoogle Scholar
  9. 9.
    Sivagangi Reddy N, Krishna Rao KSV (2016) Polymeric hydrogels: recent advances in toxic metal ion removal and anticancer drug delivery applications. Indian J Adv Chem Sci 4(2):214–234Google Scholar
  10. 10.
    Anirudhan TS, Suchithra PS, Senan P, Tharun AR (2012) Kinetic and equilibrium profiles of adsorptive recovery of thorium(IV) from aqueous solutions using poly(methacrylic acid) grafted cellulose/bentonite superabsorbent composite. Ind Eng Chem Res 51(13):4825–4836CrossRefGoogle Scholar
  11. 11.
    Yu H-R, Hu J-Q, Liu Z, Ju X-J, Xie R, Wang W, Chu L-Y (2017) Ion-recognizable hydrogels for efficient removal of cesium ions from aqueous environment. J Hazard Mater 323:632–640PubMedCrossRefGoogle Scholar
  12. 12.
    O’Neill C, Hawkes FR, Hawkes DL, Lourenço ND, Pinheiro HM, Delée W (1999) Colour in textile effluents – sources, measurement, discharge contents and simulation: a review. J Chem Technol Biotechnol 74(11):1009–1018CrossRefGoogle Scholar
  13. 13.
    Hameed BH, Din AT, Ahmad AL (2007) Adsorption of methylene blue onto bamboo-based activated carbon: kinetics and equilibrium studies. J Hazard Mater 141(3):819–825PubMedCrossRefGoogle Scholar
  14. 14.
    Raval NP, Shah PU, Shah NK (2016) Adsorptive removal of nickel(II) ions from aqueous environment: a review. J Environ Manage 179:1–20PubMedCrossRefGoogle Scholar
  15. 15.
    Souda P, Sreejith L (2015) Magnetic hydrogel for better adsorption of heavy metals from aqueous solutions. J Environ Chem Eng 3:1882–1891CrossRefGoogle Scholar
  16. 16.
    Hua R, Li Z (2014) Sulfhydryl functionalized hydrogel with magnetism: synthesis, characterization, and adsorption behavior study for heavy metal removal. Chem Eng J 249:189–200CrossRefGoogle Scholar
  17. 17.
    Zdravković AS, Nikolić LB, Ilić-Stojanović SS, Nikolić VD (2017) The application of hydrogels based on N-isopropylacrylamide and anionic comonomers. Adv Technol 6(1):33–44CrossRefGoogle Scholar
  18. 18.
    Abd El-Mohdy HL (2007) Water sorption behavior of CMC/PAM hydrogels prepared by γ-irradiation and release of potassium nitrate as agrochemical. React Funct Polym 67(10):1094–1102CrossRefGoogle Scholar
  19. 19.
    El-Tohamy WA, El-Abagy HM, Ahmed EM, Aggor FS, Hawash SI (2004) Application of super absorbent hydrogel poly(acrylate/acrylic acid) for water conservation in sandy soil. Trans Egypt Soc Chem Eng 40:1–8Google Scholar
  20. 20.
    Buwalda SJ, Boere KW, Dijkstra PJ, Feijen J, Vermonden T, Hennink WE (2014) Hydrogels in a historical perspective: from simple networks to smart materials. J Control Release 190:254–273PubMedCrossRefGoogle Scholar
  21. 21.
    Abebe DG, Fujiwara T (2012) Controlled thermoresponsive hydrogels by stereocomplexed PLA-PEG-PLA prepared via hybrid micelles of premixed copolymers with different PEG lengths. Biomacromolecules 13(6):1828–1836PubMedCrossRefGoogle Scholar
  22. 22.
    Siegel RA (2014) Stimuli sensitive polymers and self regulated drug delivery systems: a very partial review. J Control Release 190:337–351PubMedPubMedCentralCrossRefGoogle Scholar
  23. 23.
    Ilić-Stojanović S (2015) Synthesis and characterization of negatively thermosensitive hydrogels. LAP Lambert Academic Publishing, Akademikeverlag GmbH Co. KG, Saarbrücken, pp 3–40Google Scholar
  24. 24.
    Galaev IY, Mattiasson B (1999) ‘Smart’ polymers and what they could do in biotechnology and medicine. Trends Biotechnol 17(8):335–340PubMedCrossRefGoogle Scholar
  25. 25.
    Liu S, Chen F, Song X, Wu H (2017) Preparation and characterization of temperature-and pH-sensitive hemicellulose-containing hydrogels. Int J Polym Anal Charact 22(3):187–201CrossRefGoogle Scholar
  26. 26.
    Buchholz FL, Graham AT (1998) Modern superabsorbent polymer technology. Wiley-VCH, New York, pp 1–279Google Scholar
  27. 27.
    Zheng Y, Wang A (2015) Superadsorbent with three-dimensional networks: from bulk hydrogel to granular hydrogel. Eur Polym J 72:661–686CrossRefGoogle Scholar
  28. 28.
    Ahmed EM, Aggor FS, Awad AM, El-Aref AT (2013) An innovative method for preparation of nanometal hydroxide superabsorbent hydrogel. Carbohydr Polym 91(2):693–698PubMedCrossRefGoogle Scholar
  29. 29.
    Ilić-Stojanović S, Nikolić L, Nikolić V, Ristić I, Budinski-Simendić J, Kapor A, Nikolić G (2014) The structure characterization of thermosensitive poly(N-isopropylacrylamide-co-2-hydroxypropyl methacrylate) hydrogel. Polym Int 63:973–981CrossRefGoogle Scholar
  30. 30.
    Kurisawa M, Chung JE, Yang YY, Gao SJ, Uyama H (2005) Injectable biodegradable hydrogels composed of hyaluronic acid–tyramine conjugates for drug delivery and tissue engineering. Chem Commun 14(34):4312–4314CrossRefGoogle Scholar
  31. 31.
    Hu BH, Messersmith PB (2005) Enzymatically cross-linked hydrogels and their adhesive strength to biosurfaces. Orthod Craniofac Res 8(3):145–149PubMedCrossRefGoogle Scholar
  32. 32.
    Teixeira LS, Feijen J, van Blitterswijk CA, Dijkstra PJ, Karperien M (2012) Enzyme-catalyzed crosslinkable hydrogels: emerging strategies for tissue engineering. Biomaterials 33(5):1281–1290PubMedCrossRefGoogle Scholar
  33. 33.
    Tačić A, Ilić-Stojanović S, Nikolić V, Nikolić L, Zdravković A, Najman S, Stojanović S (2016) The synthesis and characterization of poly(N-isopropylacrylamide) hydrogels and residual reactants analysis. In: Book of abstracts of the XXIV Congress of Chemists and Technologists of Macedonia, Ohrid, Macedonia, 11–14 Sept 2016, p 288Google Scholar
  34. 34.
    Ilić-Stojanović S, Nikolić L, Nikolić V, Stanković M, Stamenković J, Mladenović-Ranisavljević I, Petrović SD (2012) Influence of monomer and crosslinker molar ratio on the swelling behaviour of thermosensitive hydrogels. Chem Ind Chem Eng Q 18(1):1–9CrossRefGoogle Scholar
  35. 35.
    Kou J, Fleisher D, Amidon G (1991) Release of phenylpropanolamine from dynamically swelling póly-(hydroxyethyl methacrylate-co-methacrylic acid) hydrogels. In: Cheng T, Gebelein C, Yang V (eds) Cosmetic and pharmaceutical applications of polymers. Plenum Press, New York, pp 201–208CrossRefGoogle Scholar
  36. 36.
    Nikolić L, Ilić-Stojanović S, Nikolić V (2016) Synthesis and characterization of copolymer hydrogels based on acrylic and methacrylic acid. In: Book of abstracts of the XI Conference of Chemists, Technologists and Environmentalists of the Republic of Srpska, Teslić, Bosnia and Herzegovina, 18–19 Nov 2016, p 64Google Scholar
  37. 37.
    Sawhney AS, Pathak CP, Hubbell JA (1993) Bioerodible hydrogels based on photopolymerized poly(ethylene glycol)–co-poly(α-hydroxy acid) diacrylate macromers. Macromolecules 26(4):581–587CrossRefGoogle Scholar
  38. 38.
    Baroli B (2006) Photopolymerization of biomaterials: issues and potentialities in drug delivery, tissue engineering, and cell encapsulation applications. J Chem Technol Biotechnol 81:491–499CrossRefGoogle Scholar
  39. 39.
    Nguyen KT, West JL (2002) Photopolymerizable hydrogels for tissue engineering applications. Biomaterials 23:4307–4314PubMedCrossRefPubMedCentralGoogle Scholar
  40. 40.
    Lee E, Kim B (2011) Smart delivery system for cosmetic ingredients using pH-sensitive polymer hydrogel particles. Korean J Chem Eng 28(6):1347–1350CrossRefGoogle Scholar
  41. 41.
    Danno A (1958) Gel formation of aqueous solution of polyvinyl alcohol irradiated by gamma rays from cobalt-60. J Phys Soc Jpn 13:722–727CrossRefGoogle Scholar
  42. 42.
    Stringer JL, Peppas NA (1996) Diffusion of small molecular weight drugs in radiation-crosslinked poly(ethylene oxide) hydrogels. J Control Release 42:195–202CrossRefGoogle Scholar
  43. 43.
    Kofinas P, Athanassiou V, Merrill EW (1996) Hydrogels prepared by electron irradiation of poly(ethylene oxide) in water solution: unexpected dependence of cross-link density and protein diffusion coefficients on initial PEO molecular weight. Biomaterials 17(15):1547–1550PubMedCrossRefGoogle Scholar
  44. 44.
    Liang-Chang D, Qi Y, Hoffman AS (1992) Controlled release of amylase from a thermal and pH-sensitive, macroporous hydrogel. J Control Release 19(1–3):171–177CrossRefGoogle Scholar
  45. 45.
    Wang ZC, Xu XD, Chen CS, Yun L, Song JC, Zhang XZ, Zhuo RX (2010) In situ formation of thermosensitive PNIPAAm-based hydrogels by Michael-type addition reaction. ACS Appl Mater Interfaces 2(4):1009–1018PubMedCrossRefGoogle Scholar
  46. 46.
    Xu XD, Chen CS, Wang ZC, Wang GR, Cheng SX, Zhang XZ, Zhuo RX (2008) “Click” chemistry for in situ formation of thermoresponsive P(NIPAAm-co-HEMA)-based hydrogels. J Polym Sci A 46(15):5263–5277CrossRefGoogle Scholar
  47. 47.
    Vo TN, Ekenseair AK, Kasper FK, Mikos AG (2014) Synthesis, physicochemical characterization, and cytocompatibility of bioresorbable, dual-gelling injectable hydrogels. Biomacromolecules 15:132–142PubMedCrossRefGoogle Scholar
  48. 48.
    El-Mohdy HA, Hegazy ES, Abd El-Rehim HA (2006) Characterization of starch/acrylic acid super-absorbent hydrogels prepared by ionizing radiation. J Macromol Sci A 43(7):1051–1063CrossRefGoogle Scholar
  49. 49.
    Gonçalves AA, Fonseca AC, Fabela IG, Coelho JF, Serra AC (2016) Synthesis and characterization of high performance superabsorbent hydrogels using bis[2(methacryloyloxy)ethyl] phosphate as crosslinker. Express Polym Lett 10(3):248–258CrossRefGoogle Scholar
  50. 50.
    Yu J, Yang G, Li Y, Yang W, Gao J, Lu Q (2013) Synthesis, characterization, and swelling behaviors of acrylic acid/carboxymethyl cellulose superabsorbent hydrogel by glow-discharge electrolysis plasma. Polym Eng Sci 54(10):2310–2320CrossRefGoogle Scholar
  51. 51.
    Chen J, Park H, Park K (1999) Synthesis of superporous hydrogels: hydrogels with fast swelling and superabsorbent properties. J Biomed Mater Res 44(1):53–62PubMedCrossRefGoogle Scholar
  52. 52.
    Ilić-Stojanović S, Nikolić L, Zdravković A, Nikolić V (2016) Procedure for synthesis of superapsorbing temperature and pH sensitive hydrogels. RS Patent Application 2016P01134 A1Google Scholar
  53. 53.
    Zdravković A, Nikolić L, Ilić-Stojanović S, Nikolić V, Savić S, Kapor A (2017) The evaluation of temperature and pH influences on equilibrium swelling of poly(N-isopropylacrylamide-co-acrylic acid) hydrogels. Hem Ind 71(5):395–405CrossRefGoogle Scholar
  54. 54.
    Kabiri K, Omidian H, Zohuriaan-Mehr MJ, Doroudiani S (2011) Superabsorbent hydrogel composites and nanocomposites: a review. Polym Compos 32(2):277–289CrossRefGoogle Scholar
  55. 55.
    Gupta NV, Shivakumar HG (2010) Preparation and characterization of superporous hydrogels as gastroretentive drug delivery system for rosiglitazone maleate. Daru 18(3):200–210Google Scholar
  56. 56.
    Fan YL (1995) Principles and materials development: biocompatibility and tissue response. In: Wise DL, Trantolo D, Altobelli D, Yaszemski M, Gresser J, Schwartz E (eds) Encyclopedic handbook of biomaterials and bioengineering: v. 1–2. Applications. CRC Press/Marcel Dekker, New York, pp 1331–1345Google Scholar
  57. 57.
    Himly N, Darwis D, Hardiningsih L (1993) Poly(N-vinylpyrrolidone) hydrogels: 2. Hydrogel composites as wound dressing for tropical environment. Radiat Phys Chem 42(4–6):911–914CrossRefGoogle Scholar
  58. 58.
    Kokabi M, Sirousazar M, Hassan ZM (2007) PVA–clay nanocomposite hydrogels for wound dressing. Eur Polym J 43(3):773–781CrossRefGoogle Scholar
  59. 59.
    Wu CJ, Gaharwar AK, Chan BK, Schmidt G (2011) Mechanically tough pluronic F127/laponite nanocomposite hydrogels from covalently and physically cross-linked networks. Macromolecules 44(20):8215–8224CrossRefGoogle Scholar
  60. 60.
    Durbec M, Mayer N, Vertu-Ciolino D, Disant F, Mallein-Gerin F, Perrier-Groult E (2014) Reconstruction du cartilage nasal par ingénierie tissulaire à base de polyéthylène de haute densité et d’un hydrogel. Pathol Biol 62(3):137–145PubMedCrossRefGoogle Scholar
  61. 61.
    Voldřrich Z, Tománek Z, Vacík J, Kopečcek J (1975) Long-term experience with poly(glycol monomethacrylate) gel in plastic operations of the nose. J Biomed Mater Res 9(6):675–685CrossRefGoogle Scholar
  62. 62.
    Adams TS, Crook T, Cadier MA (2007) A late complication following the insertion of hydrogel breast implants. J Plast Reconstr Aesthet Surg 60(2):210–212PubMedCrossRefGoogle Scholar
  63. 63.
    Jones L (2015) Clinical performance of a new silicone hydrogel cosmetic lens. Optometry Times, pp 1–9. http://optometrytimes.modernmedicine.com/optometrytimes/news/clinical-performance-new-silicone-hydrogel-cosmetic-lens?page=full. Accessed 10 Aug 2017
  64. 64.
    Kopecek J (2009) Hydrogels: from soft contact lenses and implants to self-assembled nanomaterials. J Polym Sci A Polym Chem 47(22):5929–5946PubMedPubMedCentralCrossRefGoogle Scholar
  65. 65.
    Wichterle O (1964) Method of manufacturing soft and flexible contact lenses. US Patent 3,496,254, 2 July 1964Google Scholar
  66. 66.
    Vashist A, Vashist A, Gupta YK, Ahmad S (2014) Recent advances in hydrogel based drug delivery systems for the human body. J Mater Chem B 2(2):147–166CrossRefGoogle Scholar
  67. 67.
    Burdick JA, Murphy WL (2012) Moving from static to dynamic complexity in hydrogel design. Nat Commun 3:1269PubMedCrossRefGoogle Scholar
  68. 68.
    Stachowiak AN, Irvine DJ (2008) Inverse opal hydrogel-collagen composite scaffolds as a supportive microenvironment for immune cell migration. J Biomed Mater Res A 85(3):815–828PubMedCrossRefGoogle Scholar
  69. 69.
    Kim JI, Kim B, Chun C, Lee SH, Song SC (2012) MRI-monitored long-term therapeutic hydrogel system for brain tumors without surgical resection. Biomaterials 33(19):4836–4842PubMedCrossRefGoogle Scholar
  70. 70.
    Wu W, Shen J, Banerjee P, Zhou S (2010) Core–shell hybrid nanogels for integration of optical temperature-sensing, targeted tumor cell imaging, and combined chemo-photothermal treatment. Biomaterials 31(29):7555–7566PubMedCrossRefGoogle Scholar
  71. 71.
    Kim JI, Lee BS, Chun C, Cho JK, Kim SY, Song SC (2012) Long-term theranostic hydrogel system for solid tumors. Biomaterials 33(7):2251–2259PubMedCrossRefGoogle Scholar
  72. 72.
    Nie G, Hah HJ, Kim G, Lee YE, Qin M, Ratani TS, Fotiadis P, Miller A, Kochi A, Gao D, Chen T (2012) Hydrogel nanoparticles with covalently linked coomassie blue for brain tumor delineation visible to the surgeon. Small 8(6):884–891PubMedCrossRefGoogle Scholar
  73. 73.
    Caldorera-Moore M, Peppas NA (2009) Micro-and nanotechnologies for intelligent and responsive biomaterial-based medical systems. Adv Drug Deliv Rev 61(15):1391–1401PubMedPubMedCentralCrossRefGoogle Scholar
  74. 74.
    Koetting MC, Peters JT, Steichen SD, Peppas NA (2015) Stimulus-responsive hydrogels: theory, modern advances, and applications. Mater Sci Eng R Rep 93:1–49PubMedPubMedCentralCrossRefGoogle Scholar
  75. 75.
    Ilić-Stojanović SS, Nikolić LB, Nikolić VD, Ilić D, Ristić IS, Tačić A (2017) Polymeric matrix systems for drug delivery. In: Keservani RK, Sharma AK, Kesharwani RK (eds) Drug delivery approaches and nanosystems, vol 1: novel drug carriers. Apple Academic Press, Waretown, pp 95–132Google Scholar
  76. 76.
    Milašinović N, Milosavljević N, Filipović J, Knežević-Jugović Z, Kalagasidis Krušić M (2010) Synthesis, characterization and application of poly(N-isopropylacrylamide-co-itaconic acid) hydrogels as supports for lipase immobilization. React Funct Polym 70(10):807–814CrossRefGoogle Scholar
  77. 77.
    Saha K, Kim J, Irwin E, Yoon J, Momin F, Trujillo V, Schaffer DV, Healy KE, Hayward RC (2010) Surface creasing instability of soft polyacrylamide cell culture substrates. Biophys J 99(12):L94–L96PubMedPubMedCentralCrossRefGoogle Scholar
  78. 78.
    Ilić-Stojanović S, Mladenović-Ranisavljević I, Nikolić V, Takić L, Stojiljković D, Stojiljković S, Nikolić L (2011) Thermo-responsive hydrogels for controlled release of paracetamol. In: 43th international October conference proceedings (Kladovo) Serbia, University of Belgrade – Technical Faculty in Bor, Bor, 12–15 Oct 2011, pp 707–710Google Scholar
  79. 79.
    Ilić-Stojanović SS, Nikolić LB, Nikolić VD, Milić JR, Petrović SD, Nikolić GM, Kapor AJ (2012) Potential application of thermo-sensitive hydrogels for controlled release of phenacetin. Hem Ind 66(6):831–839CrossRefGoogle Scholar
  80. 80.
    Ilić-Stojanović SS, Nikolić LB, Nikolić VD, Milić JR, Stamenković J, Nikolić GM, Petrović SD (2013) Synthesis and characterization of thermosensitive hydrogels and the investigation of modified release of ibuprofen. Hem Ind 67(6):901–912CrossRefGoogle Scholar
  81. 81.
    Ilić-Stojanović S, Nikolić L, Nikolić V, Petrović S, Stanković M (2014) Process for synthesis of thermosensitive hydrogels and pharmaceutical applications. RS Patent 53220, 29 Aug 2014Google Scholar
  82. 82.
    Ilić-Stojanović S, Nikolić V, Kundaković T, Savić I, Savić-Gajić I, Jocić E, Nikolić L (2018) Thermosensitive hydrogels for modified release of ellagic acid obtained from Alchemilla Vulgaris L. Extract. Int J Polym Mater Polym Biomater 67(9):553–563CrossRefGoogle Scholar
  83. 83.
    Pritchard CD, O’Shea TM, Siegwart DJ, Calo E, Anderson DG, Reynolds FM, Thomas JA, Slotkin JR, Woodard EJ, Langer R (2011) An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate. Biomaterials 32(2):587–597PubMedCrossRefGoogle Scholar
  84. 84.
    Vert M (2007) Polymeric biomaterials: strategies of the past vs. strategies of the future. Progr Colloid Polym Sci 32(8):755–761CrossRefGoogle Scholar
  85. 85.
    An SM, Ham H, Choi EJ, Shin MK, An SS, Kim HO, Koh JS (2014) Primary irritation index and safety zone of cosmetics: retrospective analysis of skin patch tests in 7440 Korean women during 12 years. Int J Cosmet Sci 36(1):62–67PubMedCrossRefGoogle Scholar
  86. 86.
  87. 87.
    Parente ME, Ochoa Andrade A, Ares G, Russo F, Jiménez-Kairuz Á (2015) Bioadhesive hydrogels for cosmetic applications. Int J Cosmet Sci 37(5):511–518PubMedCrossRefGoogle Scholar
  88. 88.
  89. 89.
    Lorenz DH (1994) A skin adhesive hydrogel, its preparation and uses Paper Manufactures Company, assignee. US Patent 5,306,504, 26 Apr 1994Google Scholar
  90. 90.
    Pal K, Banthia AK, Majumdar DK (2009) Polymeric hydrogels: characterization and biomedical applications. Des Monomers Polym 12(3):197–220CrossRefGoogle Scholar
  91. 91.
    Chien HW, Tsai WB, Jiang S (2012) Direct cell encapsulation in biodegradable and functionalizable carboxybetaine hydrogels. Biomaterials 33(23):5706–5712PubMedCrossRefGoogle Scholar
  92. 92.
    N-Isopropylacrylamide MSDS. http://www.sciencelab.com/msds.php?msdsId=9924411. Accessed 15 July 2017
  93. 93.
    Acrylic Acid MSDS. http://www.sciencelab.com/msds.php?msdsId=9922794. Accessed 15 July 2017
  94. 94.
    2,2′-Azobis(2-methylpropionitrile) MSDS. http://www.sciencelab.com/msds.php?msdsId=9922988. Accessed 15 July 2017
  95. 95.
    2-Hydroxypropyl Methacrylate MSDS. https://www.chemicalbook.com/ProductMSDSDetailCB9299748_EN.htm. Accessed 15 July 2017
  96. 96.
    Benzoyl peroxide MSDS. http://www.sciencelab.com/msds.php?msdsId=9923063. Accessed 25 June 2017
  97. 97.
    Ethylene glycol dimethacrylate MSDS. https://www.spectrumchemical.com/MSDS/E0190.PDF9923063. Accessed 25 June 2017
  98. 98.
    Methacrylic acid MSDS. http://www.sciencelab.com/msds.php?msdsId=99227949923063. Accessed 15 July 2017
  99. 99.
    Nikolić L, Ilić-Stojanović S, Nikolić V (2016) Analysis of residual reactants from synthesized poly(acrylic acid-co-methacrylic acid). In: Book of abstract of the XI Conference of Chemists, Technologists and Environmentalists of the Republic of Srpska, Teslić, Bosnia and Herzegovina, 18–19 Nov 2016, p 51Google Scholar
  100. 100.
    Araújo PH, Sayer C, Giudici R, Poco JG (2002) Techniques for reducing residual monomer content in polymers: a review. Polym Eng Sci 42(7):1442–1468CrossRefGoogle Scholar
  101. 101.
    Kostić M, Krunić N, Nikolić L, Nikolić V, Najman S, Kocić J (2009) Residual monomer content determination in some acrylic denture base materials and possibilities of its reduction. Vojnosanit Pregl 66(3):223–227PubMedCrossRefGoogle Scholar
  102. 102.
    Kostić M, Krunić N, Nikolić L, Nikolić V, Najman S, Kostić I, Rajković J, Manić M, Petković D (2011) Testing of residual monomer content reduction possibility on acrilic resins quality. Hem Ind 65(2):171–177CrossRefGoogle Scholar
  103. 103.
    Kabiri K, Hesarian S, Jamshidi A, Zohuriaan-Mehr MJ, Boohendi H, Poorheravi MR, Hashemi SA, Ahmad-Khanbeigi F (2011) Minimization of residual monomer content of superabsorbent hydrogels via alteration of initiating system. J Appl Polym Sci 120(5):2716–2723CrossRefGoogle Scholar
  104. 104.
    Hubicki Z, Kołodyńska D (2012) Selective removal of heavy metal ions from waters and waste waters using ion exchange methods. In: Kilislioğlu A (ed) Ion exchange technologies. In Tech, Rijeka, pp 193–240Google Scholar
  105. 105.
    Dave PN, Subrahmanyam N, Sharma S (2009) Kinetics and thermodynamics of copper ions removal from aqueous solution by use of activated charcoal. Indian J Chem Technol 16(3):234–239Google Scholar
  106. 106.
    Nilchi A, Dehaghan TS, Garmarodi SR (2013) Solid phase extraction of uranium and thorium on octadecyl bonded silica modified with Cyanex 302 from aqueous solutions. J Radioanal Nucl Chem 295(3):2111–2115CrossRefGoogle Scholar
  107. 107.
    Ramakrishna KR, Viraraghavan T (1997) Dye removal using low cost adsorbents. Water Sci Technol 36(2–3):189–196CrossRefGoogle Scholar
  108. 108.
    El-Hag Ali A, Shawky HA, Abd El Rehim HA, Hegazy EA (2003) Synthesis and characterization of PVP/AAc copolymer hydrogel and its applications in the removal of heavy metals from aqueous solution. Eur Polym J 39:2337–2344CrossRefGoogle Scholar
  109. 109.
    Kaşgöz H, Durmus A (2008) Dye removal by a novel hydrogel-clay nanocomposite with enhanced swelling properties. Polym Adv Technol 19:838–845CrossRefGoogle Scholar
  110. 110.
    Dai J, Yan H, Yang H, Cheng R (2010) Simple method for preparation of chitosan/poly(acrylic acid) blending hydrogel beads and adsorption of copper(II) from aqueous solutions. Chem Eng J 165:240–249CrossRefGoogle Scholar
  111. 111.
    Zdravković A, Nikolić L, Ilić-Stojanović S, Nikolić V, Savić S, Petrović S (2016) Procedure for application of temperature and pH sensitive hydrogels for the adsorption of heavy metals. RS Patent Application 2016P01203 A1Google Scholar
  112. 112.
    Wang J, Liu F, Wei J (2011) Enhanced adsorption properties of interpenetrating polymer network hydrogels for heavy metal ion removal. Polym Bull 67:1709–1720CrossRefGoogle Scholar
  113. 113.
    Roy A, Singh SK, Bajpai J, Bajpai AK (2014) Controlled pesticide release from biodegradable polymers. Cent Eur J Chem 12(4):453–469CrossRefGoogle Scholar
  114. 114.
    Bajpai AK, Giri A (2002) Swelling dynamics of a macromolecular hydrophilic network and evaluation of its potential for controlled release of agrochemicals. React Funct Polym 53:125–141CrossRefGoogle Scholar
  115. 115.
    Antić KM, Babić MM, Jovašević Vuković JJ, Vasiljević-Radović GD, Onjiac AE, Filipović JM, Tomić SLj (2015) Preparation and characterization of novel P(HEA/IA) hydrogels for Cd2+ ion removal from aqueous solution. Appl Surf Sci 338:178–189CrossRefGoogle Scholar
  116. 116.
    Li Z, Wang Y, Wu N, Chen Q, Wu K (2013) Removal of heavy metal ions from wastewater by a novel HEA/AMPS copolymer hydrogel: preparation, characterization, and mechanism. Environ Sci Pollut Res 20:1511–1525CrossRefGoogle Scholar
  117. 117.
    Lu Q, Yu J, Gao J, Yang W, Li Y (2012) A promising absorbent of acrylic acid/poly(ethylene glycol) hydrogel prepared by glow-discharge electrolysis plasma. Cent Eur J Chem 10(4):1349–1359Google Scholar
  118. 118.
    Warshawasky A (1987) Chelating ion exchangers. In: Streat M, Naden D (eds) Ion exchange and sorption processes in hydrometallurgy. Critical reports on applied chemistry. Wiley, New York, pp 166–225Google Scholar
  119. 119.
    Al-qudah YHF, Mahmoud GA, Abdel Khalek MA (2014) Radiation crosslinked poly(vinyl alcohol)/acrylic acid copolymer for removal of heavy metal ions from aqueous solutions. J Radiat Res Appl Sci 7:135–145CrossRefGoogle Scholar
  120. 120.
    Ju XJ, Zhang SB, Zhou MY, Xie R, Yang L, Chu LY (2009) Novel heavy-metal adsorption material: ion-recognition P(NIPAM-co-BCAm) hydrogels for removal of lead(II) ions. J Hazard Mater 167:114–118PubMedCrossRefGoogle Scholar
  121. 121.
    Chen JJ, Ahmad AL, Ooi BS (2013) Poly(N-isopropylacrylamide-co-acrylic acid) hydrogels for copper ion adsorption: equilibrium isotherms, kinetic and thermodynamic studies. J Environ Chem Eng 1:339–348CrossRefGoogle Scholar
  122. 122.
    Wu N, Li Z (2013) Synthesis and characterization of poly(HEA/MALA) hydrogel and its application in removal of heavy metal ions from water. Chem Eng J 215–216:894–902CrossRefGoogle Scholar
  123. 123.
    Nikolić L, Zdravković A, Ilić-Stojanović S, Nikolić V, Tačić A, Savić S, Petrović S (2017) Poly(N-isopropylacrylamide) hydrogels for removing heavy metals from solutions and adsorption procedure. RS Patent Application 2017P0106 A1Google Scholar
  124. 124.
    Tokuyama H, Iwama T (2007) Temperature-swing solid-phase extraction of heavy metals on a poly(N-isopropylacrylamide) hydrogel. Langmuir 23:13104–13108PubMedCrossRefGoogle Scholar
  125. 125.
    Tokuyama H, Iwama T (2009) Solid-phase extraction of indium(III) ions onto thermosensitive poly(N-isopropylacrylamide). Sep Purif Technol 68:417–421CrossRefGoogle Scholar
  126. 126.
    Barati A, Moghadam EA, Miri T, Asgari M (2014) Rapid removal of heavy metal cations by novel nanocomposite hydrogels based on wheat bran and clinoptilolite: kinetics, thermodynamics, and isotherms. Water Air Soil Pollut 225:2096CrossRefGoogle Scholar
  127. 127.
    Gao T, Wang W, Wang A (2011) A pH-sensitive composite hydrogel based on sodium alginate and medical stone: synthesis, swelling, and heavy metal ions adsorption properties. Macromol Res 19(7):739–748CrossRefGoogle Scholar
  128. 128.
    Irani M, Ismail H, Ahmad Z, Fan M (2015) Synthesis of linear low-density polyethylene-g-poly (acrylic acid)-co-starch/organo-montmorillonite hydrogel composite as an adsorbent for removal of Pb(ΙΙ) from aqueous solutions. J Environ Sci 27:9–20CrossRefGoogle Scholar
  129. 129.
    Hazer O, Kartal S (2010) Use of amidoximated hydrogel for removal and recovery of U(VI) ion from water samples. Talanta 82:1974–1979PubMedCrossRefGoogle Scholar
  130. 130.
    Taşdelen B, Osmanlioglu AE, Kam E (2013) The adsorption behavior of cesium on poly(N-isopropylacrylamide/itaconic acid) copolymeric hydrogels. Polym Bull 70(11):3041–3053CrossRefGoogle Scholar
  131. 131.
    Yi X, Xu Z, Liu Y, Guo X, Ou M, Xu X (2017) Highly efficient removal of uranium(VI) from wastewater by polyacrylic acid hydrogels. RSC Adv 7:6278–6287CrossRefGoogle Scholar
  132. 132.
    Didehban K, Hayasi M, Kermajani F (2017) Removal of anionic dyes from aqueous solutions using polyacrylamide and polyacrylic acid hydrogels. Korean J Chem Eng 34(4):1177–1186CrossRefGoogle Scholar
  133. 133.
    Mekewi MA, Madkour TM, Darwish AS, Hashish YM (2015) Does poly(acrylic acid-co-acrylamide) hydrogel be the pluperfect choiceness in treatment of dyeing wastewater? “From simple copolymer to gigantic aqua-waste remover”. J Ind Eng Chem 30:359–371CrossRefGoogle Scholar
  134. 134.
    Corona-Rivera MA, Ovando-Medina VM, Bernal-Jacome LA, Cervantes-González E, Antonio-Carmona ID, Dávila-Guzmán NE (2017) Remazol red dye removal using poly(acrylamide-co-acrylic acid) hydrogels and water absorbency studies. Colloid Polym Sci 295(1):227–236CrossRefGoogle Scholar
  135. 135.
    Li P, Siddaramaiah, Kim NH, Yoo G-H, Lee J-H (2009) Poly(acrylamide/laponite) nanocomposite hydrogels: swelling and cationic dye adsorption properties. J Appl Polym Sci 111:1786–1798CrossRefGoogle Scholar
  136. 136.
    Aref L, Navarchian AH, Dadkhah D (2017) Adsorption of crystal violet dye from aqueous solution by poly(acrylamide-co-maleic acid)/montmorillonite nanocomposite. J Polym Environ 25:628–639CrossRefGoogle Scholar
  137. 137.
    Shirsath SR, Patil AP, Patil R, Naik JB, Gogate PR, Sonawane SH (2013) Removal of Brilliant Green from wastewater using conventional and ultrasonically prepared poly(acrylic acid) hydrogel loaded with kaolin clay: a comparative study. Ultrason Sonochem 20(3):914–923PubMedCrossRefGoogle Scholar
  138. 138.
    Fradj AB, Lafi R, Hamouda SB, Gzara L, Hamzaoui AH, Hafiane A (2014) Effect of chemical parameters on the interaction between cationic dyes and poly(acrylic acid). J Photochem Photobiol A Chem 284:49–54CrossRefGoogle Scholar
  139. 139.
    Üzüm OB, Karadağ E (2006) Synthetic polymeric absorbent for dye based on chemically crosslinked acrylamide/mesaconic acid hydrogels. J Appl Polym Sci 101:405–413CrossRefGoogle Scholar
  140. 140.
    Nesic AR, Panic VV, Onjia AE, Velickovic SJ (2015) The enhanced removal of cationic dyes in binary system using novel copolymers with two kinds of acidic groups. Colloids Surf A Physicochem Eng Asp 476:24–34CrossRefGoogle Scholar
  141. 141.
    Bhattacharyya R, Ray SK (2015) Adsorption of industrial dyes by semi-IPN hydrogels of acrylic copolymers and sodium alginate. J Ind Eng Chem 22:92–102CrossRefGoogle Scholar
  142. 142.
    Kazanskii KS, Dubrovskii SA (1992) Chemistry and physics of “agricultural” hydrogels. In: Abe A, Dušek K, Kobayashi S (eds) Polyelectrolytes hydrogels chromatographic materials, vol 104. Springer Berlin Heidelberg, Berlin, pp 97–133CrossRefGoogle Scholar
  143. 143.
    Teodorescu M, Lungu A, Stanescu PO, Neamţu C (2009) Preparation and properties of novel slow-release NPK agrochemical formulations based on poly(acrylic acid) hydrogels and liquid fertilizers. Ind Eng Chem Res 48:6527–6534CrossRefGoogle Scholar
  144. 144.
    Saraydin D, Karadağ E, Güven O (1998) The releases of agrochemicals from radiation induced acrylamide/crotonic acid hydrogels. Polym Bull 41(5):577–584CrossRefGoogle Scholar
  145. 145.
    Saraydin D, Karadağ E, Güven O (2000) Relationship between the swelling process and the releases of water soluble agrochemicals from radiation crosslinked acrylamide/itaconic acid copolymers. Polym Bull 45(3):287–294CrossRefGoogle Scholar
  146. 146.
    Wang H, Wang Z, Zhu B (2007) Preparation and properties of new non-loading and superhigh ammonium nitrate loading hydrogels. React Funct Polym 67:225–232CrossRefGoogle Scholar
  147. 147.
    Mahdavinia GR, Mousavi SB, Karimi F, Marandi GB, Garabaghi H, Shahabvand S (2009) Synthesis of porous poly(acrylamide) hydrogels using calcium carbonate and its application for slow release of potassium nitrate. Express Polym Lett 3(5):279–285CrossRefGoogle Scholar
  148. 148.
    Rudzinski WE, Chipuk T, Dave AM, Kumbar SG, Aminabhavi TM (2003) pH-sensitive acrylic-based copolymeric hydrogels for the controlled release of a pesticide and a micronutrient. J Appl Polym Sci 87:394–403CrossRefGoogle Scholar
  149. 149.
    Maziad NA, Abou El Fadl FI, El-Kelesh NA, El-Hamouly SH, Zeid IF, Gayed HM (2016) Radiation synthesis and characterization of super absorbent hydrogels for controlled release of some agrochemicals. J Radioanal Nucl Chem 307:513–521CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Ljubiša B. Nikolić
    • 1
  • Aleksandar S. Zdravković
    • 2
  • Vesna D. Nikolić
    • 1
  • Snežana S. Ilić-Stojanović
    • 1
  1. 1.Faculty of TechnologyUniversity of NišLeskovacSerbia
  2. 2.Vocational High School for Technology and ArtLeskovacSerbia

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