Considerations for Medications Commonly Utilized in the Oncology Population in the Intensive Care Unit

  • Anne Rain Tanner BrownEmail author
  • Michelle Horng
  • Terri Lynn Shigle
Reference work entry


An increasing number of oncologic patients are presenting to the intensive care unit with complications from both their chronic disease states and cancer therapies due to improved survival rates. The management of these patients is complex due to immunosuppression (from the malignancy and/or treatment), metabolic complications, and diverse medication regimens with the potential for significant drug-drug interactions and overlapping adverse effects. This chapter will provide clinicians with an overview of non-chemotherapy medications frequently encountered in the critically ill oncologic patient, with a focus on practical considerations.


Oncology Critical care Cancer Drug interactions Pharmacology Intensive care Critically ill Drug monitoring Adverse events Immunocompromised 


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Copyright information

© This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2020

Authors and Affiliations

  • Anne Rain Tanner Brown
    • 1
    Email author
  • Michelle Horng
    • 1
  • Terri Lynn Shigle
    • 2
    • 3
  1. 1.Critical Care/Nutrition SupportThe University of Texas MD Anderson Cancer CenterHoustonUSA
  2. 2.OncologyThe University of Texas MD Anderson Cancer CenterHoustonUSA
  3. 3.Stem Cell Transplantation and Cellular TherapyThe University of Texas MD Anderson Cancer CenterHoustonUSA

Section editors and affiliations

  • Todd W. Canada
    • 1
  • Jeffrey J. Bruno
    • 2
  1. 1.Clinical Pharmacy Svcs, Pharmacy Clinical ProgramsThe University of Texas MD Anderson Cancer CenterHoustonUSA
  2. 2.Clinical Pharmacy Specialist – Critical Care / Nutrition SupportThe University of Texas MD Anderson Cancer CenterHoustonUSA

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