Practical Approach to the Critically Ill Obstetric Patient with an Oncological Disease

  • Sandra OlayaEmail author
  • Paula Velásquez
  • Jacobo Bustamante
Reference work entry


Cancer during pregnancy is a term to define the tumors diagnosed during the 1st week of pregnancy or until the 1st year after delivery, which is a tough challenge for diagnosis because of the physiological changes that occur during pregnancy, additional to the therapeutic difficulty generated by the conflict between the optimal maternal treatment and fetal development. The decision-making when to initiate a therapeutic management such as chemotherapy, radiotherapy or the imminent need of induced abortion. In the management of these patients, assistance and interdisciplinary support is required, which includes a neonatologist, perinatologist, oncologist, obstetrician, intensivist, toxicologist, and psychologist.


Pregnancy complications Critical care Melanoma Breast neoplasms Uterine cervical neoplasms Ovarian neoplasms 


  1. 1.
    Pavlidis NA. Coexistence of pregnancy and malignancy. Oncologist. 2002;7:279–87.CrossRefGoogle Scholar
  2. 2.
    Amant F, Halaska M, Fumagalli M, et al. Gynecologic cancers in pregnancy. Int J Gynecol Cancer. 2014;24:394–403. Scholar
  3. 3.
    Corredor E, Castillo M. Cancer en mujeres embarazadas y su extensión a la unidad fetoplacentaria. Rev Col Obst Gin. 2007;58(3):232–6.Google Scholar
  4. 4.
    Dotters-Katz S, McNeil M, Limmer J, Kuller J. Cancer and pregnancy. Obstet Gynecol Surv. 2014;69:277–86. Scholar
  5. 5.
    Pearl J, Price R, Richardson W, Fanelli R. Guidelines for diagnosis, treatment, and use of laparoscopy for surgical problems during pregnancy. Surg Endosc. 2011;25:3479–92. Scholar
  6. 6.
    ACOG committee opinion no. 474: nonobstetric surgery during pregnancy. Obstet Gynecol. 2011;117:420–1.
  7. 7.
    Guyatt G, Akl E, Crowther M, et al. Executive summary: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of chest physicians evidence-based clinical practice guidelines. Chest. 2012;141:7S–47S. Scholar
  8. 8.
    Ali S, Gupta S, Sehgal R, Vogel V. Survival outcomes in pregnancy associated breast cancer: a retrospective case control study. Breast J. 2012;18:139–44. Scholar
  9. 9.
    Azim H, Santoro L, Russell-Edu W, et al. Prognosis of pregnancy-associated breast cancer: a meta-analysis of 30 studies. Cancer Treat Rev. 2012;38:834–42. Scholar
  10. 10.
    Pettersson B, Andersson S, Hellman K, Hellström A. Invasive carcinoma of the uterine cervix associated with pregnancy. Cancer. 2010; NA-NA.
  11. 11.
    El-Messidi A, Patenaude V, Abenhaim H. Incidence and outcomes of women with non-Hodgkin's lymphoma in pregnancy: a population-based study on 7.9 million births. J Obstet Gynaecol Res. 2014;41:582–9. Scholar
  12. 12.
    Bachanova V, Connors J. Hodgkin lymphoma in pregnancy. Curr Hematol Malig Rep. 2013;8:211–7. Scholar
  13. 13.
    Horowitz N, Benyamini N, Wohlfart K, et al. Reproductive organ involvement in non-Hodgkin lymphoma during pregnancy: a systematic review. Lancet Oncol. 2013;14:e275–82. Scholar
  14. 14.
    Colbourn DS, Nathanson L, Belilos E. Pregnancy and malignant melanoma. Semin Oncol. 1989;16(5):377–87.PubMedGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Sandra Olaya
    • 1
    Email author
  • Paula Velásquez
    • 1
  • Jacobo Bustamante
    • 1
  1. 1.Universidad Tecnológica de Pereira y Hospital Universitario San Jorge (HUSJ)PereiraColombia

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