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Sepsis and Septic Shock in Cancer Patients

  • Imrana MalikEmail author
  • Joseph L. Nates
Reference work entry

Abstract

Cancer is one of the most common comorbid medical conditions present among sepsis patients. Although sepsis-related mortality rates in cancer patients are decreasing over time, similar to the general population, their incidence and mortality rates still remain unacceptably high. Because of their underlying cancer diagnoses and immunologic states, cancer patients require special attention and have unique considerations for the treatment and management of sepsis. In addition, new and emerging cancer therapeutics bring additional challenges in the management of sepsis in cancer patients. This chapter begins with a discussion regarding the current dynamics related to sepsis terminology and then covers the prevailing understanding of sepsis epidemiology, etiology, and pathophysiology. Finally, the clinical aspects of diagnosis, management, and prognosis are presented, which are largely based on studies in the general population and have been extrapolated for the cancer patient.

Keywords

Sepsis Cancer Septic shock SIRS qSOFA 

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of Critical CareThe University of Texas MD Anderson Cancer CenterHoustonUSA
  2. 2.Department of Critical Care and Respiratory CareThe University of Texas MD Anderson Cancer CenterHoustonUSA

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