Encyclopedia of Gerontology and Population Aging

Living Edition
| Editors: Danan Gu, Matthew E. Dupre

Familial Dyslipidemias

  • Carlos Alberto Aguilar SalinasEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-3-319-69892-2_728-1



Dyslipidemias is a group of asymptomatic disorders identifiable by the presence of abnormal concentrations of cholesterol, triglycerides, and HDL cholesterol caused by an abnormal composition and/or number of plasma lipoproteins. They are a major risk factor for having atherosclerotic cardiovascular disease; its treatment has been highly effective to reduce cardiovascular mortality (Catapano et al. 2016).


Lipoproteins are complex structures that transport lipids in their interior to make it soluble in the aqueous media of plasma (Durrington 2003). Lipid transport has two destinations. The first route transports lipids from the sites of production or absorption (intestine and liver) to the tissues where they are used or stored (muscle, fat, glands, etc.). In the case of the liver, the lipoprotein synthesis takes 8–12 h and it is highly regulated by insulin and the fatty...

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Unidad de Investigación en Enfermedades MetabólicasInstituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico CityMexico
  2. 2.Departamento de Endocrinología y MetabolismoInstituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico CityMexico
  3. 3.Escuela de Medicina y Ciencias de la SaludTecnologico de MonterreyMonterreyMexico

Section editors and affiliations

  • Diddahally R. Govindaraju
    • 1
    • 2
  1. 1.Department of Human Evolutionary Biology, Museum of Comparative ZoologyHarvard UniversityCambridgeUSA
  2. 2.The Institute for Aging Research, The Glenn Center for the Biology of Human AgingAlbert Einstein College of MedicineBronxUSA