Consortium on Interplay of Genes and Environment Across Multiple Studies
The Interplay of Genes and Environment across Multiple Studies (IGEMS) group is a consortium of longitudinal twin studies of adult development and aging established a decade ago to explore the nature of social context effects and gene-environment interplay in late-life functioning. The combined data contains information from over 50,000 individual participants aged 25–102 at baseline (including nearly 20,000 complete twin pairs) with median follow-up of 9.5 years. Studies include measures of aging-relevant outcomes in three broad domains: physical health and functional ability, psychological well-being (emotional stability/depression), and cognitive health. Studies also include multiple indicators of the social environment, spanning early childhood through late adulthood, and, by virtue of different nationalities and birth years, encompass different environmental contexts with respect to healthcare, retirement systems, and other social policies.
Research has firmly established...
IGEMS is funded by NIH grants No. R01 AG037985, R01 AG059329, and R01 AG060470.
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