Treatment of Chronic Hand Eczema: Other Immunomodulating Therapies

  • Rodrigo da Mota
  • Bernhard HomeyEmail author
Reference work entry


The management of chronic hand eczema is challenging and includes several behavioral and medical measures. A subset of patient will not respond to topical treatment strategies alone, but may benefit from systemic therapy. In this chapter, selected immunomodulating drugs (azathioprin, cyclosporine, methotrexate) which have been successfully used for the systemic treatment of chronic hand eczema is reviewed regarding their clinical pharmacology, mechanisms of action, efficacy, and safety.


Chronic hand eczema Immunomodulating drugs Methotrexate Cyclosporine A Azathioprine 


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© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of DermatologyUniversity Hospital DuesseldorfDuesseldorfGermany

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