Encyclopedia of Signaling Molecules

2018 Edition
| Editors: Sangdun Choi

Aurora Kinases

  • David Reboutier
  • Claude Prigent
Reference work entry
DOI: https://doi.org/10.1007/978-3-319-67199-4_81

Aurora Kinases Family Members and their Synonyms

Aurora-A: AIK, ARK1, AURA, AURORA2, BTAK, MGC34538, STK15, STK6, STK7

Aurora-B: AIK2, AIM-1, AIM1, ARK2, AurB, IPL1, STK12, STK5

Aurora-C: AIE2, AIK3, ARK3, AurC, STK13, Aurora-C

Historical Background

Every new cell is generated through division of an existing cell (one cell generates two cells), and survival of all organisms depends on reliable transmission of the genetic information from the mother cell to daughter cells. Consequently, all cellular components must be duplicated before cell divides, and these duplications must be achieved with extreme precision and reliability over generations. The eukaryotic cell (cell with a nucleus) has set up complex network of regulatory mechanisms to ensure a correct sequence of events that eventually leads to cell division. This network called the cell cycle control system consists mainly in a complex assembly of oscillating phosphorylation/dephosphorylation reactions. Several protein kinases and...

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References

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Centre National de la Recherche Scientifique, Unité Mixte de Recherche UMR 6290RennesFrance
  2. 2.Université Rennes 1, Institut de Génétique et Développement de RennesRennesFrance